MYL12-AS1

Summary

MYL12-AS1 (MYL12A and MYL12B antisense RNA 1, HGNC:55331) is a long non-coding RNA gene on chromosome 18p11.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55331
Approved symbol	MYL12-AS1
Name	MYL12A and MYL12B antisense RNA 1
Location	18p11.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000264235
Ensembl biotype	lncRNA
Entrez	104968399
RNAcentral	URS0000D5764B — lncRNA, 1031 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000578800, ENST00000581905, ENST00000781691, ENST00000781692, ENST00000781693, ENST00000781694, ENST00000781695

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578800 — 3 exons

Exon	Start	End
ENSE00002709423	3255436	3255838
ENSE00002713194	3256242	3256322
ENSE00004153954	3261272	3262058

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 88.60.

FANTOM5 (CAGE): breadth broad, TPM avg 1.5819 / max 46.4618, expressed in 614 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
171012	1.3242	549
171013	0.2076	71
171014	0.0501	14

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	88.60	gold quality
testis	UBERON:0000473	88.09	gold quality
right testis	UBERON:0004534	86.77	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.61	gold quality
heart left ventricle	UBERON:0002084	83.32	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.62	gold quality
heart	UBERON:0000948	78.93	gold quality
apex of heart	UBERON:0002098	78.63	gold quality
right atrium auricular region	UBERON:0006631	77.28	gold quality
hindlimb stylopod muscle	UBERON:0004252	76.86	gold quality
granulocyte	CL:0000094	76.26	gold quality
spleen	UBERON:0002106	70.72	gold quality
mucosa of transverse colon	UBERON:0004991	70.67	gold quality
bone marrow cell	CL:0002092	69.22	silver quality
lower esophagus mucosa	UBERON:0035834	69.01	gold quality
right lobe of liver	UBERON:0001114	68.98	gold quality
bone marrow	UBERON:0002371	68.61	gold quality
right lung	UBERON:0002167	68.26	gold quality
lymph node	UBERON:0000029	68.08	gold quality
subcutaneous adipose tissue	UBERON:0002190	67.65	gold quality
skeletal muscle tissue	UBERON:0001134	67.52	gold quality
left coronary artery	UBERON:0001626	67.32	gold quality
muscle of leg	UBERON:0001383	67.08	gold quality
metanephros cortex	UBERON:0010533	67.02	gold quality
adipose tissue	UBERON:0001013	66.89	gold quality
gastrocnemius	UBERON:0001388	66.75	gold quality
blood	UBERON:0000178	66.59	gold quality
liver	UBERON:0002107	66.52	gold quality
descending thoracic aorta	UBERON:0002345	66.43	gold quality
omental fat pad	UBERON:0010414	66.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.