MYO18B-AS1

Summary

MYO18B-AS1 (MYO18B antisense RNA 1, HGNC:40831) is a long non-coding RNA gene on chromosome 22q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40831
Approved symbol	MYO18B-AS1
Name	MYO18B antisense RNA 1
Location	22q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231933
Ensembl biotype	lncRNA
Entrez	105372963
RNAcentral	URS0000811CE3 — lncRNA, 1575 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000453457, ENST00000593715, ENST00000594542, ENST00000594585, ENST00000594856, ENST00000595093, ENST00000595102, ENST00000596813, ENST00000597284, ENST00000597548, ENST00000597614, ENST00000599080, ENST00000599792, ENST00000600211, ENST00000600269, ENST00000600903, ENST00000607895, ENST00000608115, ENST00000608257, ENST00000608507, ENST00000608921, ENST00000609157, ENST00000609275, ENST00000609570, ENST00000609809, ENST00000609820, ENST00000609823, ENST00000609889, ENST00000828740

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453457 — 6 exons

Exon	Start	End
ENSE00002994793	25884716	25884883
ENSE00003031406	25899716	25899884
ENSE00003033174	25892227	25892640
ENSE00003210562	25895111	25895268
ENSE00003705478	25900825	25901042
ENSE00003767719	25876854	25877301

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 87.76.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.76	gold quality
left testis	UBERON:0004533	81.52	gold quality
testis	UBERON:0000473	81.14	gold quality
skeletal muscle tissue	UBERON:0001134	80.57	gold quality
right testis	UBERON:0004534	80.41	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.78	gold quality
bone marrow cell	CL:0002092	73.26	silver quality
hindlimb stylopod muscle	UBERON:0004252	70.61	gold quality
calcaneal tendon	UBERON:0003701	63.95	gold quality
sural nerve	UBERON:0015488	63.70	silver quality
bone marrow	UBERON:0002371	60.91	gold quality
ganglionic eminence	UBERON:0004023	59.19	gold quality
right atrium auricular region	UBERON:0006631	58.53	gold quality
muscle of leg	UBERON:0001383	58.18	gold quality
gastrocnemius	UBERON:0001388	57.24	gold quality
monocyte	CL:0000576	57.13	gold quality
heart	UBERON:0000948	56.62	gold quality
heart left ventricle	UBERON:0002084	54.21	gold quality
liver	UBERON:0002107	53.21	silver quality
superior frontal gyrus	UBERON:0002661	52.50	gold quality
blood	UBERON:0000178	52.49	gold quality
multicellular organism	UBERON:0000468	51.99	gold quality
prefrontal cortex	UBERON:0000451	51.77	gold quality
ascending aorta	UBERON:0001496	51.47	gold quality
stromal cell of endometrium	CL:0002255	50.85	silver quality
thoracic aorta	UBERON:0001515	50.83	gold quality
urinary bladder	UBERON:0001255	50.39	gold quality
apex of heart	UBERON:0002098	49.99	gold quality
right frontal lobe	UBERON:0002810	49.69	gold quality
smooth muscle tissue	UBERON:0001135	49.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.