MYRACL

Summary

MYRACL (myelination regulating oligodendrocyte associated lncRNA, HGNC:53467) is a long non-coding RNA gene on chromosome 5q14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53467
Approved symbol	MYRACL
Name	myelination regulating oligodendrocyte associated lncRNA
Location	5q14.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.163, CTD-2316B1
Ensembl gene	ENSG00000249362
Ensembl biotype	lncRNA
Entrez	111082994
RNAcentral	URS0000BC44FC — lncRNA, 921 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000504287, ENST00000655396, ENST00000815382, ENST00000815383, ENST00000815384, ENST00000815385, ENST00000815386, ENST00000815387, ENST00000815388, ENST00000815389, ENST00000815390, ENST00000815391, ENST00000815392, ENST00000815393, ENST00000815394, ENST00000815395, ENST00000815396, ENST00000815397, ENST00000815398, ENST00000815399

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504287 — 2 exons

Exon	Start	End
ENSE00004217319	87661992	87662113
ENSE00004217336	87678568	87680021

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 84.99.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1904 / max 39.0235, expressed in 41 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
57477	0.1904	41

Top tissues by expression

53 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.99	gold quality
cortical plate	UBERON:0005343	81.54	gold quality
ganglionic eminence	UBERON:0004023	79.27	gold quality
ventricular zone	UBERON:0003053	67.37	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.81	gold quality
endometrium	UBERON:0001295	58.84	silver quality
prefrontal cortex	UBERON:0000451	54.93	gold quality
thyroid gland	UBERON:0002046	53.20	gold quality
saliva-secreting gland	UBERON:0001044	52.55	gold quality
blood	UBERON:0000178	52.20	gold quality
monocyte	CL:0000576	52.10	gold quality
superior frontal gyrus	UBERON:0002661	50.54	gold quality
frontal cortex	UBERON:0001870	50.18	gold quality
heart left ventricle	UBERON:0002084	50.14	gold quality
calcaneal tendon	UBERON:0003701	49.81	silver quality
cerebral cortex	UBERON:0000956	49.26	gold quality
primary visual cortex	UBERON:0002436	48.89	silver quality
Brodmann (1909) area 9	UBERON:0013540	48.81	gold quality
anterior cingulate cortex	UBERON:0009835	48.22	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	48.14	gold quality
right hemisphere of cerebellum	UBERON:0014890	47.66	gold quality
brain	UBERON:0000955	47.32	gold quality
cerebellar cortex	UBERON:0002129	45.89	gold quality
cerebellum	UBERON:0002037	45.85	gold quality
cerebellar hemisphere	UBERON:0002245	45.37	gold quality
islet of Langerhans	UBERON:0000006	45.10	silver quality
right frontal lobe	UBERON:0002810	44.99	gold quality
amygdala	UBERON:0001876	44.86	gold quality
substantia nigra	UBERON:0002038	44.83	gold quality
corpus callosum	UBERON:0002336	44.77	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.