MYREM

Summary

MYREM (MYBPC2 cis regulating lncRNA enhancer of myogenesis, HGNC:56685) is a long non-coding RNA gene on chromosome 19q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56685
Approved symbol	MYREM
Name	MYBPC2 cis regulating lncRNA enhancer of myogenesis
Location	19q13.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	Charme, lncFAM, HSCHARME, lncFAM71E1-2:2
Ensembl gene	ENSG00000268518
Ensembl biotype	lncRNA
Entrez	128266840
RNAcentral	URS00026A2836 — lncRNA, 1881 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000595005, ENST00000702023, ENST00000702920, ENST00000821317, ENST00000821318, ENST00000821319

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000595005 — 3 exons

Exon	Start	End
ENSE00003010734	50487392	50487706
ENSE00003011156	50486560	50487188
ENSE00004029922	50500276	50500339

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 95.87.

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	95.87	gold quality
muscle of leg	UBERON:0001383	94.47	gold quality
gastrocnemius	UBERON:0001388	93.98	gold quality
apex of heart	UBERON:0002098	90.41	gold quality
left lobe of thyroid gland	UBERON:0001120	89.00	gold quality
right atrium auricular region	UBERON:0006631	88.80	gold quality
right lobe of thyroid gland	UBERON:0001119	88.16	gold quality
thyroid gland	UBERON:0002046	86.98	gold quality
cardiac atrium	UBERON:0002081	86.63	gold quality
tibialis anterior	UBERON:0001385	86.45	silver quality
quadriceps femoris	UBERON:0001377	82.92	silver quality
skeletal muscle tissue	UBERON:0001134	82.86	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	81.67	gold quality
heart left ventricle	UBERON:0002084	81.02	gold quality
cardiac ventricle	UBERON:0002082	79.90	gold quality
spinal cord	UBERON:0002240	79.66	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	79.30	silver quality
heart	UBERON:0000948	79.15	gold quality
putamen	UBERON:0001874	79.08	gold quality
muscle tissue	UBERON:0002385	78.86	gold quality
bone marrow cell	CL:0002092	76.83	gold quality
deltoid	UBERON:0001476	76.41	silver quality
substantia nigra	UBERON:0002038	76.07	gold quality
amygdala	UBERON:0001876	74.38	gold quality
midbrain	UBERON:0001891	74.12	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.36	gold quality
caudate nucleus	UBERON:0001873	71.46	gold quality
right frontal lobe	UBERON:0002810	70.90	gold quality
monocyte	CL:0000576	70.42	gold quality
oviduct epithelium	UBERON:0004804	70.31	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.