MYT1L-AS1

Summary

MYT1L-AS1 (MYT1L antisense RNA 1, HGNC:49274) is a long non-coding RNA gene on chromosome 2p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49274
Approved symbol	MYT1L-AS1
Name	MYT1L antisense RNA 1
Location	2p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225619
Ensembl biotype	lncRNA
Entrez	730811
RNAcentral	URS000075B7F4 — lncRNA, 3242 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000422175, ENST00000448106

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422175 — 2 exons

Exon	Start	End
ENSE00001613058	2324097	2327110
ENSE00001748858	2319232	2319383

Expression profiles

Bgee: expression breadth broad, 24 present calls, max score 59.06.

Top tissues by expression

24 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ganglionic eminence	UBERON:0004023	59.06	gold quality
cortical plate	UBERON:0005343	58.95	silver quality
prefrontal cortex	UBERON:0000451	51.43	silver quality
cerebral cortex	UBERON:0000956	47.91	silver quality
superior frontal gyrus	UBERON:0002661	47.38	silver quality
primary visual cortex	UBERON:0002436	46.35	silver quality
corpus callosum	UBERON:0002336	45.48	silver quality
islet of Langerhans	UBERON:0000006	45.02	silver quality
brain	UBERON:0000955	44.83	silver quality
hypothalamus	UBERON:0001898	43.86	gold quality
blood	UBERON:0000178	43.44	silver quality
right frontal lobe	UBERON:0002810	41.47	silver quality
nucleus accumbens	UBERON:0001882	41.23	silver quality
cerebellar hemisphere	UBERON:0002245	41.08	silver quality
right hemisphere of cerebellum	UBERON:0014890	40.46	silver quality
Ammon’s horn	UBERON:0001954	40.03	silver quality
testis	UBERON:0000473	38.78	gold quality
left testis	UBERON:0004533	38.78	gold quality
caudate nucleus	UBERON:0001873	37.92	silver quality
right testis	UBERON:0004534	37.51	gold quality
pituitary gland	UBERON:0000007	37.01	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	36.12	silver quality
substantia nigra	UBERON:0002038	34.67	silver quality
gastrocnemius	UBERON:0001388	32.83	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.