NAALADL2-AS2

Summary

NAALADL2-AS2 (NAALADL2 antisense RNA 2, HGNC:41015) is a long non-coding RNA gene on chromosome 3q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41015
Approved symbol	NAALADL2-AS2
Name	NAALADL2 antisense RNA 2
Location	3q26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226779
Ensembl biotype	lncRNA
Entrez	100874244
RNAcentral	URS0000759C6B — lncRNA, 807 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000424690

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424690 — 3 exons

Exon	Start	End
ENSE00001732366	175271057	175271096
ENSE00001777434	175234861	175235809
ENSE00001800740	175242382	175242430

Expression profiles

Bgee: expression breadth broad, 70 present calls, max score 66.71.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0108 / max 3.3259, expressed in 8 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
45658	0.0108	8

Top tissues by expression

70 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	66.71	gold quality
prefrontal cortex	UBERON:0000451	57.07	gold quality
tonsil	UBERON:0002372	56.90	silver quality
blood	UBERON:0000178	54.32	silver quality
monocyte	CL:0000576	53.18	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	52.67	gold quality
calcaneal tendon	UBERON:0003701	50.53	silver quality
liver	UBERON:0002107	50.41	silver quality
placenta	UBERON:0001987	49.78	gold quality
cortex of kidney	UBERON:0001225	49.08	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	48.41	gold quality
kidney	UBERON:0002113	48.16	silver quality
stomach	UBERON:0000945	46.98	silver quality
left coronary artery	UBERON:0001626	46.97	gold quality
lymph node	UBERON:0000029	46.93	silver quality
islet of Langerhans	UBERON:0000006	46.71	gold quality
smooth muscle tissue	UBERON:0001135	46.56	silver quality
superior frontal gyrus	UBERON:0002661	46.31	silver quality
adult mammalian kidney	UBERON:0000082	46.17	silver quality
lung	UBERON:0002048	45.86	gold quality
right lobe of liver	UBERON:0001114	45.73	silver quality
gastrocnemius	UBERON:0001388	45.72	gold quality
endometrium	UBERON:0001295	45.23	gold quality
thoracic mammary gland	UBERON:0005200	44.57	gold quality
tibial artery	UBERON:0007610	44.42	gold quality
body of stomach	UBERON:0001161	44.01	silver quality
intestine	UBERON:0000160	44.00	silver quality
heart	UBERON:0000948	43.59	silver quality
urinary bladder	UBERON:0001255	43.44	silver quality
heart left ventricle	UBERON:0002084	43.39	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.