NAMA

Summary

NAMA (non-protein coding RNA, associated with MAP kinase pathway and growth arrest, HGNC:42408) is a long non-coding RNA gene on chromosome 9q22.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42408
Approved symbol	NAMA
Name	non-protein coding RNA, associated with MAP kinase pathway and growth arrest
Location	9q22.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	STX17-AS1
Ensembl gene	ENSG00000271086
Ensembl biotype	lncRNA
OMIM	620412
Entrez	100996569
RNAcentral	URS000075A0F7 — lncRNA, 2233 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 78 — 78 lncRNA

ENST00000427039, ENST00000529965, ENST00000603491, ENST00000604009, ENST00000604237, ENST00000604258, ENST00000605043, ENST00000605377, ENST00000605707, ENST00000649719, ENST00000652827, ENST00000655615, ENST00000657190, ENST00000659797, ENST00000662355, ENST00000700913, ENST00000701493, ENST00000701763, ENST00000701815, ENST00000715772, ENST00000715777, ENST00000725614, ENST00000725615, ENST00000725616, ENST00000725617, ENST00000725618, ENST00000725619, ENST00000725620, ENST00000725621, ENST00000725622, ENST00000725623, ENST00000725624, ENST00000725625, ENST00000725626, ENST00000725627, ENST00000725628, ENST00000725629, ENST00000725630, ENST00000725631, ENST00000725632, ENST00000725633, ENST00000725634, ENST00000725635, ENST00000725636, ENST00000725637, ENST00000725638, ENST00000725639, ENST00000725640, ENST00000725641, ENST00000725642, ENST00000725643, ENST00000725644, ENST00000725645, ENST00000725646, ENST00000725647, ENST00000725648, ENST00000725649, ENST00000725650, ENST00000725651, ENST00000725652, ENST00000725653, ENST00000725654, ENST00000725655, ENST00000725656, ENST00000725657, ENST00000725658, ENST00000725659, ENST00000725660, ENST00000725661, ENST00000725662, ENST00000725663, ENST00000725664, ENST00000725665, ENST00000725666, ENST00000725667, ENST00000725668, ENST00000725669, ENST00000725670

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427039 — 7 exons

Exon	Start	End
ENSE00001607561	99586885	99586984
ENSE00001650884	99588425	99588586
ENSE00001654207	99805871	99805991
ENSE00001683043	99585786	99586650
ENSE00001754955	99596190	99596287
ENSE00004027895	99819821	99819889
ENSE00004027898	99718159	99718287

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 88.44.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4029 / max 25.4789, expressed in 125 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
101723	0.3924	121
101722	0.0105	3

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.44	gold quality
bone marrow cell	CL:0002092	76.62	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.41	gold quality
right testis	UBERON:0004534	69.29	gold quality
left testis	UBERON:0004533	68.81	gold quality
gastrocnemius	UBERON:0001388	68.73	gold quality
testis	UBERON:0000473	68.63	gold quality
skeletal muscle tissue	UBERON:0001134	68.22	gold quality
muscle of leg	UBERON:0001383	67.99	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.36	gold quality
right hemisphere of cerebellum	UBERON:0014890	64.58	gold quality
cortical plate	UBERON:0005343	64.45	gold quality
cerebellar hemisphere	UBERON:0002245	64.15	gold quality
cerebellar cortex	UBERON:0002129	64.12	gold quality
tonsil	UBERON:0002372	64.10	silver quality
cerebellum	UBERON:0002037	64.04	gold quality
nucleus accumbens	UBERON:0001882	63.68	gold quality
pituitary gland	UBERON:0000007	61.74	gold quality
ventricular zone	UBERON:0003053	61.64	gold quality
corpus callosum	UBERON:0002336	61.57	gold quality
ganglionic eminence	UBERON:0004023	61.39	gold quality
right atrium auricular region	UBERON:0006631	61.39	gold quality
bone marrow	UBERON:0002371	61.26	gold quality
temporal lobe	UBERON:0001871	61.21	gold quality
amygdala	UBERON:0001876	61.10	gold quality
hypothalamus	UBERON:0001898	60.85	gold quality
adenohypophysis	UBERON:0002196	60.81	gold quality
anterior cingulate cortex	UBERON:0009835	60.77	gold quality
brain	UBERON:0000955	60.73	gold quality
caudate nucleus	UBERON:0001873	60.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.