NAPA-AS1

Summary

NAPA-AS1 (NAPA antisense RNA 1, HGNC:44118) is a long non-coding RNA gene on chromosome 19q13.32-q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44118
Approved symbol	NAPA-AS1
Name	NAPA antisense RNA 1
Location	19q13.32-q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000268061
Ensembl biotype	lncRNA
Entrez	100505681
RNAcentral	URS000075DEA4 — lncRNA, 656 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000593284, ENST00000594367, ENST00000746421, ENST00000746422, ENST00000746423

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000593284 — 3 exons

Exon	Start	End
ENSE00003093012	47484282	47484524
ENSE00003114922	47495028	47496382
ENSE00003189019	47493447	47493601

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 78.03.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.6505 / max 27.0833, expressed in 1285 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
176690	1.5345	948
176692	1.0243	655
176691	0.0918	22

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
body of pancreas	UBERON:0001150	78.03	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.78	gold quality
bone marrow cell	CL:0002092	75.73	gold quality
pancreas	UBERON:0001264	74.14	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	72.66	gold quality
mucosa of transverse colon	UBERON:0004991	72.65	gold quality
sural nerve	UBERON:0015488	72.23	gold quality
right uterine tube	UBERON:0001302	71.96	gold quality
colonic epithelium	UBERON:0000397	71.53	silver quality
hindlimb stylopod muscle	UBERON:0004252	71.26	gold quality
body of stomach	UBERON:0001161	71.24	gold quality
ventricular zone	UBERON:0003053	71.13	gold quality
right adrenal gland	UBERON:0001233	70.65	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.65	gold quality
right atrium auricular region	UBERON:0006631	70.55	gold quality
apex of heart	UBERON:0002098	70.50	gold quality
right adrenal gland cortex	UBERON:0035827	70.34	gold quality
leukocyte	CL:0000738	70.16	gold quality
monocyte	CL:0000576	70.14	gold quality
granulocyte	CL:0000094	70.05	gold quality
left adrenal gland cortex	UBERON:0035825	69.97	gold quality
cardiac atrium	UBERON:0002081	69.78	gold quality
right hemisphere of cerebellum	UBERON:0014890	69.67	gold quality
cerebellar hemisphere	UBERON:0002245	69.59	gold quality
cerebellar cortex	UBERON:0002129	69.58	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.51	gold quality
left adrenal gland	UBERON:0001234	69.41	gold quality
muscle of leg	UBERON:0001383	69.26	gold quality
heart left ventricle	UBERON:0002084	69.21	gold quality
gastrocnemius	UBERON:0001388	69.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.