NAV2-AS2

Summary

NAV2-AS2 (NAV2 antisense RNA 2, HGNC:40743) is a long non-coding RNA gene on chromosome 11p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40743
Approved symbol	NAV2-AS2
Name	NAV2 antisense RNA 2
Location	11p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254453
Ensembl biotype	lncRNA
Entrez	100874014
RNAcentral	URS000075B555 — lncRNA, 853 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000533767, ENST00000791630

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000533767 — 2 exons

Exon	Start	End
ENSE00004172926	20048974	20049477
ENSE00004172927	20043444	20044297

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 96.79.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0667 / max 14.2586, expressed in 26 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
119002	0.0248	12
119003	0.0166	10
206224	0.0124	8
119000	0.0071	4
119001	0.0058	4

Top tissues by expression

227 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
apex of heart	UBERON:0002098	96.79	gold quality
left ventricle myocardium	UBERON:0006566	95.82	gold quality
cardiac muscle of right atrium	UBERON:0003379	93.62	gold quality
right atrium auricular region	UBERON:0006631	92.05	gold quality
cardiac atrium	UBERON:0002081	91.95	gold quality
heart left ventricle	UBERON:0002084	90.67	gold quality
cardiac ventricle	UBERON:0002082	90.42	gold quality
myocardium	UBERON:0002349	90.16	gold quality
heart	UBERON:0000948	88.12	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.88	gold quality
heart right ventricle	UBERON:0002080	83.69	gold quality
hindlimb stylopod muscle	UBERON:0004252	77.27	gold quality
vena cava	UBERON:0004087	67.61	silver quality
body of uterus	UBERON:0009853	65.03	gold quality
colonic epithelium	UBERON:0000397	64.78	silver quality
gastrocnemius	UBERON:0001388	63.41	gold quality
muscle of leg	UBERON:0001383	63.00	gold quality
body of pancreas	UBERON:0001150	62.64	gold quality
right lung	UBERON:0002167	62.63	gold quality
bone marrow cell	CL:0002092	62.58	silver quality
smooth muscle tissue	UBERON:0001135	60.84	gold quality
pancreas	UBERON:0001264	59.93	gold quality
cortical plate	UBERON:0005343	59.92	gold quality
tibialis anterior	UBERON:0001385	57.25	silver quality
myometrium	UBERON:0001296	55.89	gold quality
prefrontal cortex	UBERON:0000451	55.87	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
epithelial cell of pancreas	CL:0000083	53.43	gold quality
uterus	UBERON:0000995	52.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.37

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.