NAV2-AS4

Summary

NAV2-AS4 (NAV2 antisense RNA 4, HGNC:40741) is a long non-coding RNA gene on chromosome 11p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40741
Approved symbol	NAV2-AS4
Name	NAV2 antisense RNA 4
Location	11p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254622
Ensembl biotype	lncRNA
Entrez	399876
RNAcentral	URS000075BDC1 — lncRNA, 1369 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000532874, ENST00000837121, ENST00000837122, ENST00000837123

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000532874 — 3 exons

Exon	Start	End
ENSE00002143852	19510890	19511724
ENSE00002150609	19518397	19518595
ENSE00002190719	19519750	19519896

Expression profiles

Bgee: expression breadth broad, 75 present calls, max score 80.98.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0083 / max 6.7727, expressed in 3 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
118990	0.0047	3
118991	0.0035	3

Top tissues by expression

186 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tibialis anterior	UBERON:0001385	80.98	silver quality
ileal mucosa	UBERON:0000331	76.23	silver quality
cardiac muscle of right atrium	UBERON:0003379	76.23	gold quality
left ventricle myocardium	UBERON:0006566	76.16	gold quality
upper arm skin	UBERON:0004263	75.03	gold quality
pancreatic ductal cell	CL:0002079	74.89	silver quality
bone marrow cell	CL:0002092	73.09	gold quality
mucosa of paranasal sinus	UBERON:0005030	66.61	gold quality
kidney epithelium	UBERON:0004819	65.15	gold quality
epithelial cell of pancreas	CL:0000083	64.60	gold quality
oocyte	CL:0000023	64.03	gold quality
placenta	UBERON:0001987	64.03	gold quality
nasal cavity epithelium	UBERON:0005384	63.07	gold quality
epithelium of nasopharynx	UBERON:0001951	62.40	gold quality
sural nerve	UBERON:0015488	62.31	silver quality
myocardium	UBERON:0002349	61.91	gold quality
muscle of leg	UBERON:0001383	61.85	silver quality
corpus callosum	UBERON:0002336	61.55	gold quality
deltoid	UBERON:0001476	61.07	gold quality
quadriceps femoris	UBERON:0001377	60.41	gold quality
colonic epithelium	UBERON:0000397	59.29	silver quality
vastus lateralis	UBERON:0001379	58.20	gold quality
superficial temporal artery	UBERON:0001614	57.83	gold quality
pigmented layer of retina	UBERON:0001782	57.80	gold quality
metanephros	UBERON:0000081	56.27	silver quality
epithelium of mammary gland	UBERON:0003244	55.04	gold quality
bronchial epithelial cell	CL:0002328	54.88	gold quality
mammary duct	UBERON:0001765	54.87	gold quality
calcaneal tendon	UBERON:0003701	54.80	gold quality
bronchus	UBERON:0002185	54.61	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.