NAV2-AS5

Summary

NAV2-AS5 (NAV2 antisense RNA 5, HGNC:40740) is a long non-coding RNA gene on chromosome 11p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40740
Approved symbol	NAV2-AS5
Name	NAV2 antisense RNA 5
Location	11p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255043
Ensembl biotype	lncRNA
Entrez	100874012
RNAcentral	URS000075AF97 — lncRNA, 3336 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000528726, ENST00000530652

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000528726 — 3 exons

Exon	Start	End
ENSE00002159551	19502672	19503858
ENSE00002173920	19505239	19507229
ENSE00002180326	19504285	19504413

Expression profiles

Bgee: expression breadth broad, 72 present calls, max score 78.39.

Top tissues by expression

178 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	78.39	gold quality
bone marrow cell	CL:0002092	76.54	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	71.75	gold quality
sperm	CL:0000019	63.82	silver quality
corpus callosum	UBERON:0002336	61.15	gold quality
cortical plate	UBERON:0005343	60.60	silver quality
colonic epithelium	UBERON:0000397	59.85	silver quality
ventricular zone	UBERON:0003053	58.42	silver quality
buccal mucosa cell	CL:0002336	56.96	gold quality
calcaneal tendon	UBERON:0003701	55.77	gold quality
monocyte	CL:0000576	51.66	silver quality
tendon	UBERON:0000043	50.24	silver quality
right testis	UBERON:0004534	50.14	gold quality
adrenal gland	UBERON:0002369	48.71	gold quality
left testis	UBERON:0004533	48.54	gold quality
testis	UBERON:0000473	47.88	gold quality
right lobe of liver	UBERON:0001114	47.27	silver quality
pancreas	UBERON:0001264	47.26	silver quality
stomach	UBERON:0000945	46.81	silver quality
bone marrow	UBERON:0002371	46.46	gold quality
right lobe of thyroid gland	UBERON:0001119	45.87	gold quality
thyroid gland	UBERON:0002046	45.74	gold quality
omental fat pad	UBERON:0010414	44.28	gold quality
peritoneum	UBERON:0002358	44.25	gold quality
heart left ventricle	UBERON:0002084	44.03	gold quality
adult mammalian kidney	UBERON:0000082	43.96	gold quality
adipose tissue of abdominal region	UBERON:0007808	43.75	gold quality
body of pancreas	UBERON:0001150	43.69	silver quality
prefrontal cortex	UBERON:0000451	43.66	silver quality
left lobe of thyroid gland	UBERON:0001120	43.47	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.42

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long noncoding RNA NAV2-AS5 relieves chondrocyte inflammation by targeting miR-8082/TNIP2 in osteoarthritis. (PMID:36503346)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.