NAV3-AS1

Summary

NAV3-AS1 (NAV3 antisense RNA 1, HGNC:58287) is a long non-coding RNA gene on chromosome 12q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58287
Approved symbol	NAV3-AS1
Name	NAV3 antisense RNA 1
Location	12q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258225
Ensembl biotype	lncRNA
Entrez	139432812
RNAcentral	URS0000537899 — lncRNA, 475 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000549103

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000549103 — 4 exons

Exon	Start	End
ENSE00002325165	78091511	78091737
ENSE00002398304	78088767	78088814
ENSE00002401439	78052181	78052220
ENSE00002408926	78056185	78056344

Expression profiles

Bgee: expression breadth broad, 88 present calls, max score 88.41.

Top tissues by expression

88 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.41	gold quality
sural nerve	UBERON:0015488	72.27	gold quality
liver	UBERON:0002107	68.57	silver quality
primary visual cortex	UBERON:0002436	63.89	gold quality
stromal cell of endometrium	CL:0002255	61.66	gold quality
corpus callosum	UBERON:0002336	61.42	gold quality
lymph node	UBERON:0000029	61.40	gold quality
islet of Langerhans	UBERON:0000006	57.21	gold quality
cortex of kidney	UBERON:0001225	56.68	gold quality
prefrontal cortex	UBERON:0000451	55.50	gold quality
superior frontal gyrus	UBERON:0002661	55.07	gold quality
adrenal tissue	UBERON:0018303	54.42	gold quality
blood	UBERON:0000178	54.06	gold quality
leukocyte	CL:0000738	52.25	silver quality
monocyte	CL:0000576	51.20	silver quality
kidney	UBERON:0002113	50.40	gold quality
muscle of leg	UBERON:0001383	50.39	gold quality
gastrocnemius	UBERON:0001388	49.65	gold quality
heart left ventricle	UBERON:0002084	49.51	gold quality
right adrenal gland	UBERON:0001233	49.37	gold quality
frontal cortex	UBERON:0001870	49.25	gold quality
myometrium	UBERON:0001296	49.10	gold quality
right adrenal gland cortex	UBERON:0035827	49.01	gold quality
stomach	UBERON:0000945	48.53	gold quality
adrenal gland	UBERON:0002369	48.01	gold quality
small intestine	UBERON:0002108	47.43	gold quality
cerebellar cortex	UBERON:0002129	47.08	silver quality
heart	UBERON:0000948	47.03	gold quality
cerebellar hemisphere	UBERON:0002245	46.72	silver quality
endometrium	UBERON:0001295	46.61	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.