NCAM1-AS1

Summary

NCAM1-AS1 (NCAM1 antisense RNA 1, HGNC:48675) is a long non-coding RNA gene on chromosome 11q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48675
Approved symbol	NCAM1-AS1
Name	NCAM1 antisense RNA 1
Location	11q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227487
Ensembl biotype	lncRNA
Entrez	100288346
RNAcentral	URS000075B7BD — lncRNA, 713 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000526229, ENST00000533638, ENST00000661168, ENST00000662696

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000526229 — 2 exons

Exon	Start	End
ENSE00002170793	113273624	113273901
ENSE00002194413	113269719	113270521

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 82.77.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0506 / max 27.3995, expressed in 10 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
122334	0.0506	10

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	82.77	gold quality
cerebellum	UBERON:0002037	79.12	gold quality
cerebellar cortex	UBERON:0002129	78.95	gold quality
cerebellar hemisphere	UBERON:0002245	78.86	gold quality
cortical plate	UBERON:0005343	69.54	gold quality
sural nerve	UBERON:0015488	69.53	gold quality
body of uterus	UBERON:0009853	69.36	gold quality
myometrium	UBERON:0001296	68.90	gold quality
lower esophagus muscularis layer	UBERON:0035833	68.90	gold quality
lower esophagus	UBERON:0013473	68.79	gold quality
superior frontal gyrus	UBERON:0002661	67.71	gold quality
left ovary	UBERON:0002119	67.54	gold quality
corpus callosum	UBERON:0002336	67.17	gold quality
left uterine tube	UBERON:0001303	66.81	gold quality
ovary	UBERON:0000992	66.51	gold quality
urinary bladder	UBERON:0001255	66.18	gold quality
right ovary	UBERON:0002118	66.12	gold quality
apex of heart	UBERON:0002098	65.98	gold quality
ganglionic eminence	UBERON:0004023	65.72	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.58	gold quality
right frontal lobe	UBERON:0002810	65.28	gold quality
muscle layer of sigmoid colon	UBERON:0035805	65.17	gold quality
primary visual cortex	UBERON:0002436	65.02	gold quality
ectocervix	UBERON:0012249	64.95	gold quality
ventricular zone	UBERON:0003053	64.52	gold quality
frontal cortex	UBERON:0001870	64.41	gold quality
heart left ventricle	UBERON:0002084	64.39	gold quality
brain	UBERON:0000955	63.54	gold quality
left adrenal gland	UBERON:0001234	63.47	gold quality
prefrontal cortex	UBERON:0000451	63.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.