NCF4-AS1

Summary

NCF4-AS1 (NCF4 antisense RNA 1, HGNC:40393) is a long non-coding RNA gene on chromosome 22q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40393
Approved symbol	NCF4-AS1
Name	NCF4 antisense RNA 1
Location	22q12.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTA-833B7.2
Ensembl gene	ENSG00000183822
Ensembl biotype	lncRNA
Entrez	107985578
RNAcentral	URS0000BC44BC — lncRNA, 997 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000431290, ENST00000619915, ENST00000805861, ENST00000805862, ENST00000805863, ENST00000805864, ENST00000805865, ENST00000805866

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000431290 — 2 exons

Exon	Start	End
ENSE00004198492	36856781	36858243
ENSE00004198503	36870093	36870486

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 83.23.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0894 / max 15.3729, expressed in 45 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
193978	0.0894	45

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.23	gold quality
blood	UBERON:0000178	77.92	gold quality
bone marrow cell	CL:0002092	73.80	silver quality
granulocyte	CL:0000094	70.07	gold quality
bone marrow	UBERON:0002371	66.95	gold quality
colonic epithelium	UBERON:0000397	64.79	silver quality
spleen	UBERON:0002106	64.26	gold quality
leukocyte	CL:0000738	63.90	gold quality
monocyte	CL:0000576	63.56	gold quality
placenta	UBERON:0001987	61.61	gold quality
skeletal muscle tissue	UBERON:0001134	60.59	gold quality
tonsil	UBERON:0002372	58.59	gold quality
lymph node	UBERON:0000029	58.50	gold quality
duodenum	UBERON:0002114	58.22	gold quality
vermiform appendix	UBERON:0001154	56.75	gold quality
right coronary artery	UBERON:0001625	56.70	gold quality
gall bladder	UBERON:0002110	55.93	gold quality
liver	UBERON:0002107	53.73	silver quality
rectum	UBERON:0001052	53.02	gold quality
left uterine tube	UBERON:0001303	51.61	gold quality
multicellular organism	UBERON:0000468	51.26	gold quality
small intestine	UBERON:0002108	50.62	gold quality
small intestine Peyer’s patch	UBERON:0003454	50.06	gold quality
muscle of leg	UBERON:0001383	49.71	gold quality
cortex of kidney	UBERON:0001225	49.46	gold quality
gastrocnemius	UBERON:0001388	49.33	gold quality
upper lobe of left lung	UBERON:0008952	49.24	gold quality
descending thoracic aorta	UBERON:0002345	49.17	gold quality
right lobe of liver	UBERON:0001114	48.90	silver quality
right ovary	UBERON:0002118	48.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.