NCK2-AS1

Summary

NCK2-AS1 (NCK2 antisense RNA 1, HGNC:40394) is a long non-coding RNA gene on chromosome 2q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40394
Approved symbol	NCK2-AS1
Name	NCK2 antisense RNA 1
Location	2q12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235522
Ensembl biotype	lncRNA
Entrez	139355212
RNAcentral	URS0000770234 — lncRNA, 893 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000427050, ENST00000596418, ENST00000598281, ENST00000613614, ENST00000615184, ENST00000618432

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427050 — 3 exons

Exon	Start	End
ENSE00001596193	105854503	105855273
ENSE00001690308	105857133	105857177
ENSE00001693760	105856670	105856746

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 86.72.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.72	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.56	gold quality
sural nerve	UBERON:0015488	74.05	gold quality
colonic epithelium	UBERON:0000397	73.26	gold quality
cortical plate	UBERON:0005343	72.40	gold quality
ganglionic eminence	UBERON:0004023	71.41	gold quality
skeletal muscle tissue	UBERON:0001134	71.17	gold quality
adrenal tissue	UBERON:0018303	70.99	gold quality
bone marrow cell	CL:0002092	70.48	silver quality
tonsil	UBERON:0002372	69.25	gold quality
muscle tissue	UBERON:0002385	68.67	gold quality
ventricular zone	UBERON:0003053	66.79	gold quality
lower esophagus mucosa	UBERON:0035834	65.67	gold quality
blood	UBERON:0000178	65.39	gold quality
bone marrow	UBERON:0002371	65.17	gold quality
calcaneal tendon	UBERON:0003701	63.75	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.27	gold quality
corpus callosum	UBERON:0002336	61.86	gold quality
placenta	UBERON:0001987	61.27	gold quality
testis	UBERON:0000473	61.07	gold quality
right testis	UBERON:0004534	60.97	gold quality
left testis	UBERON:0004533	60.56	gold quality
duodenum	UBERON:0002114	59.92	gold quality
monocyte	CL:0000576	59.77	gold quality
mucosa of transverse colon	UBERON:0004991	59.72	gold quality
granulocyte	CL:0000094	59.56	gold quality
urinary bladder	UBERON:0001255	58.93	gold quality
liver	UBERON:0002107	57.95	gold quality
esophagus mucosa	UBERON:0002469	57.33	gold quality
kidney	UBERON:0002113	56.92	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.