NCKAP5-AS2

Summary

NCKAP5-AS2 (NCKAP5 antisense RNA 2, HGNC:54065) is a long non-coding RNA gene on chromosome 2q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54065
Approved symbol	NCKAP5-AS2
Name	NCKAP5 antisense RNA 2
Location	2q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226953
Ensembl biotype	lncRNA
Entrez	101928161
RNAcentral	URS000075D3F7 — lncRNA, 531 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000432414, ENST00000454699, ENST00000606428, ENST00000670944, ENST00000760483

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432414 — 5 exons

Exon	Start	End
ENSE00001608884	133266195	133266296
ENSE00001718750	133268356	133268442
ENSE00001759202	133284695	133284762
ENSE00001781354	133268916	133269041
ENSE00001796402	133267273	133267424

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 75.43.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	75.43	gold quality
stromal cell of endometrium	CL:0002255	71.92	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.47	gold quality
colonic epithelium	UBERON:0000397	68.95	silver quality
superior frontal gyrus	UBERON:0002661	67.79	gold quality
ganglionic eminence	UBERON:0004023	66.65	gold quality
prefrontal cortex	UBERON:0000451	66.41	gold quality
frontal cortex	UBERON:0001870	65.80	gold quality
anterior cingulate cortex	UBERON:0009835	65.57	gold quality
hypothalamus	UBERON:0001898	65.18	gold quality
cerebral cortex	UBERON:0000956	65.06	gold quality
islet of Langerhans	UBERON:0000006	64.78	gold quality
right frontal lobe	UBERON:0002810	64.77	gold quality
duodenum	UBERON:0002114	64.76	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	64.60	gold quality
ventricular zone	UBERON:0003053	64.41	gold quality
substantia nigra	UBERON:0002038	64.24	gold quality
Brodmann (1909) area 9	UBERON:0013540	63.87	gold quality
corpus callosum	UBERON:0002336	63.59	gold quality
placenta	UBERON:0001987	63.50	gold quality
Ammon’s horn	UBERON:0001954	63.34	gold quality
adenohypophysis	UBERON:0002196	62.91	gold quality
amygdala	UBERON:0001876	62.55	gold quality
pituitary gland	UBERON:0000007	62.41	gold quality
brain	UBERON:0000955	62.25	gold quality
skeletal muscle tissue	UBERON:0001134	61.84	gold quality
left ovary	UBERON:0002119	61.77	gold quality
spleen	UBERON:0002106	61.09	gold quality
primary visual cortex	UBERON:0002436	60.83	gold quality
ovary	UBERON:0000992	60.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.