NDUFA6-DT

Summary

NDUFA6-DT (NDUFA6 divergent transcript, HGNC:45273) is a long non-coding RNA gene on chromosome 22q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45273
Approved symbol	NDUFA6-DT
Name	NDUFA6 divergent transcript
Location	22q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237037
Ensembl biotype	lncRNA
Entrez	100132273
RNAcentral	URS000075D607 — lncRNA, 1678 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 12 lncRNA, 4 retained_intron

ENST00000417327, ENST00000434834, ENST00000439129, ENST00000451451, ENST00000536447, ENST00000547929, ENST00000595777, ENST00000600968, ENST00000608643, ENST00000608974, ENST00000609499, ENST00000609833, ENST00000610250, ENST00000617009, ENST00000617396, ENST00000621190

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417327 — 4 exons

Exon	Start	End
ENSE00001733015	42091297	42091600
ENSE00001769824	42090956	42091181
ENSE00002336041	42124047	42124562
ENSE00002406222	42124875	42125349

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 97.60.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.1998 / max 123.5973, expressed in 1437 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
192557	4.9754	1428
192558	0.2244	86

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	97.60	gold quality
liver	UBERON:0002107	94.60	gold quality
right hemisphere of cerebellum	UBERON:0014890	94.14	gold quality
cerebellum	UBERON:0002037	93.67	gold quality
cerebellar hemisphere	UBERON:0002245	93.66	gold quality
cerebellar cortex	UBERON:0002129	93.63	gold quality
right testis	UBERON:0004534	92.90	gold quality
sural nerve	UBERON:0015488	92.63	gold quality
left testis	UBERON:0004533	92.56	gold quality
testis	UBERON:0000473	91.60	gold quality
cortical plate	UBERON:0005343	90.23	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.07	gold quality
right uterine tube	UBERON:0001302	89.45	gold quality
pituitary gland	UBERON:0000007	88.81	gold quality
right frontal lobe	UBERON:0002810	88.71	gold quality
frontal cortex	UBERON:0001870	88.13	gold quality
right lobe of thyroid gland	UBERON:0001119	88.04	gold quality
prefrontal cortex	UBERON:0000451	87.78	gold quality
primary visual cortex	UBERON:0002436	87.73	gold quality
left ovary	UBERON:0002119	87.71	gold quality
superior frontal gyrus	UBERON:0002661	87.56	gold quality
left lobe of thyroid gland	UBERON:0001120	87.48	gold quality
thyroid gland	UBERON:0002046	87.39	gold quality
small intestine Peyer’s patch	UBERON:0003454	87.25	gold quality
brain	UBERON:0000955	87.13	gold quality
adenohypophysis	UBERON:0002196	87.11	gold quality
ovary	UBERON:0000992	87.06	gold quality
small intestine	UBERON:0002108	86.92	gold quality
cerebral cortex	UBERON:0000956	86.89	gold quality
anterior cingulate cortex	UBERON:0009835	86.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.