NDUFC1

Summary

NDUFC1 (NADH:ubiquinone oxidoreductase subunit C1, HGNC:7705) is a protein-coding gene on chromosome 4q31.1, encoding NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial (O43677). Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. It is a selective cancer dependency (DepMap: 16.5% of cell lines).

The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants.

Source: NCBI Gene 4717 — RefSeq curated summary.

At a glance

• Clinical variants (ClinVar): 24 total
• Druggable target: yes
• Cancer dependency (DepMap): dependent in 16.5% of screened cell lines
• MANE Select transcript: NM_001184989

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:7705
Approved symbol	NDUFC1
Name	NADH:ubiquinone oxidoreductase subunit C1
Location	4q31.1
Locus type	gene with protein product
Status	Approved
Aliases	KFYI
Ensembl gene	ENSG00000109390
Ensembl biotype	protein_coding
OMIM	603844
Entrez	4717

Gene structure

Transcript identifiers

Ensembl transcripts: 67 — 62 protein_coding, 4 protein_coding_CDS_not_defined, 1 nonsense_mediated_decay

ENST00000394223, ENST00000394225, ENST00000394228, ENST00000503453, ENST00000503997, ENST00000505036, ENST00000507764, ENST00000513022, ENST00000539002, ENST00000539387, ENST00000544855, ENST00000676245, ENST00000854294, ENST00000854295, ENST00000854296, ENST00000854297, ENST00000854298, ENST00000854299, ENST00000854300, ENST00000854301, ENST00000854302, ENST00000854303, ENST00000854304, ENST00000854305, ENST00000854306, ENST00000854307, ENST00000854308, ENST00000854309, ENST00000854310, ENST00000854311, ENST00000854312, ENST00000854313, ENST00000854314, ENST00000854315, ENST00000854316, ENST00000854317, ENST00000854318, ENST00000920492, ENST00000920493, ENST00000920494, ENST00000920495, ENST00000920496, ENST00000920497, ENST00000920498, ENST00000920499, ENST00000920500, ENST00000920501, ENST00000920502, ENST00000920503, ENST00000920504, ENST00000920505, ENST00000920506, ENST00000920507, ENST00000920508, ENST00000920509, ENST00000920510, ENST00000920511, ENST00000920512, ENST00000920513, ENST00000920514, ENST00000920515, ENST00000959733, ENST00000959734, ENST00000959735, ENST00000959736, ENST00000959737, ENST00000959738

RefSeq mRNA: 7 — MANE Select: NM_001184989 NM_001184986, NM_001184987, NM_001184988, NM_001184989, NM_001184990, NM_001184991, NM_002494

CCDS: CCDS3746

Canonical transcript exons

ENST00000394223 — 6 exons

Exon	Start	End
ENSE00001517793	139289931	139290092
ENSE00001517794	139302416	139302477
ENSE00002058322	139297385	139297443
ENSE00003527591	139292530	139292609
ENSE00003532122	139295043	139295146
ENSE00003532724	139295732	139295960

Expression profiles

Bgee: expression breadth ubiquitous, 294 present calls, max score 99.46.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 135.4493 / max 728.1735, expressed in 1827 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
54058	123.5371	1826
54062	7.7957	1723
54061	1.7328	886
54060	1.5668	712
54063	0.5400	292
54059	0.2768	95

Top tissues by expression

295 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
renal medulla	UBERON:0000362	99.46	gold quality
heart right ventricle	UBERON:0002080	99.42	gold quality
diaphragm	UBERON:0001103	99.28	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	99.27	gold quality
biceps brachii	UBERON:0001507	99.19	gold quality
type B pancreatic cell	CL:0000169	99.16	gold quality
body of tongue	UBERON:0011876	99.13	gold quality
nephron tubule	UBERON:0001231	99.08	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	99.08	gold quality
vastus lateralis	UBERON:0001379	99.03	gold quality
pigmented layer of retina	UBERON:0001782	98.90	gold quality
vena cava	UBERON:0004087	98.84	gold quality
tongue	UBERON:0001723	98.81	gold quality
triceps brachii	UBERON:0001509	98.76	gold quality
pharyngeal mucosa	UBERON:0000355	98.73	gold quality
cardia of stomach	UBERON:0001162	98.71	gold quality
renal glomerulus	UBERON:0000074	98.66	gold quality
metanephric glomerulus	UBERON:0004736	98.66	gold quality
hair follicle	UBERON:0002073	98.65	gold quality
cervix epithelium	UBERON:0004801	98.64	gold quality
cardiac ventricle	UBERON:0002082	98.59	gold quality
tongue squamous epithelium	UBERON:0006919	98.58	gold quality
pylorus	UBERON:0001166	98.57	gold quality
cerebellar vermis	UBERON:0004720	98.57	gold quality
adult organism	UBERON:0007023	98.57	gold quality
heart left ventricle	UBERON:0002084	98.56	gold quality
pons	UBERON:0000988	98.55	gold quality
postcentral gyrus	UBERON:0002581	98.54	gold quality
mucosa of sigmoid colon	UBERON:0004993	98.53	gold quality
superior surface of tongue	UBERON:0007371	98.50	gold quality

Single-cell (SCXA)

Detected in 6 experiment(s), a significant marker in 4.

Experiment	Marker?	Max mean expression
E-HCAD-10	yes	33.65
E-MTAB-6701	yes	16.45
E-GEOD-135922	yes	9.19
E-MTAB-6819	no	827.01
E-CURD-97	no	331.27
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

19 targeting NDUFC1, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-6833-3P	100.00	70.63	3197
HSA-MIR-4768-5P	100.00	69.49	2861
HSA-MIR-548AW	99.99	72.57	3559
HSA-MIR-1468-3P	99.96	72.74	3797
HSA-MIR-548AJ-5P	99.78	71.12	3085
HSA-MIR-548F-5P	99.78	71.02	3093
HSA-MIR-548G-5P	99.78	71.12	3085
HSA-MIR-548X-5P	99.78	71.12	3085
HSA-MIR-5580-5P	99.38	66.96	1139
HSA-MIR-520A-5P	99.35	66.72	1632
HSA-MIR-525-5P	99.35	66.85	1615
HSA-MIR-10522-5P	99.26	68.50	2087
HSA-MIR-5690	99.25	67.58	1012
HSA-MIR-4705	99.10	69.10	1091
HSA-MIR-421	98.90	67.04	1883
HSA-MIR-6074	98.89	69.64	2187
HSA-MIR-12125	98.59	67.54	1044
HSA-MIR-1322	97.98	68.96	625
HSA-MIR-9851-5P	97.57	67.49	1067

Functional genomics

DepMap (CRISPR cell-line fitness): dependent in 16.5% of screened cell lines.

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Ndufc1	ENSMUSG00000037152
rattus_norvegicus	Ndufc1	ENSRNOG00000089477

Protein

Protein identifiers

NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial — O43677 (reviewed: O43677)

Alternative names: Complex I-KFYI, NADH-ubiquinone oxidoreductase KFYI subunit

All UniProt accessions (2): O43677, A0A6Q8PHK7

UniProt curated annotations — full annotation on UniProt →

Function. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subunit / interactions. Complex I is composed of 45 different subunits.

Subcellular location. Mitochondrion inner membrane.

Similarity. Belongs to the complex I NDUFC1 subunit family.

RefSeq proteins (7): NP_001171915, NP_001171916, NP_001171917, NP_001171918, NP_001171919, NP_001171920, NP_002485 (=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR026192	NDUFC1	Family

Pfam: PF15088

UniProt features (3 total): transit peptide 1, chain 1, transmembrane region 1

Structure

Experimental structures (PDB)

7 structures.

PDB	Method	Resolution (Å)
9I4I	ELECTRON MICROSCOPY	2.63
9TI4	ELECTRON MICROSCOPY	2.66
9CWT	ELECTRON MICROSCOPY	3.44
5XTC	ELECTRON MICROSCOPY	3.7
5XTD	ELECTRON MICROSCOPY	3.7
5XTH	ELECTRON MICROSCOPY	3.9
5XTI	ELECTRON MICROSCOPY	17.4

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-O43677-F1	83.60	0.50

Function

Pathways and Gene Ontology

Reactome pathways

4 pathways

ID	Pathway
R-HSA-611105	Respiratory electron transport
R-HSA-6799198	Complex I biogenesis
R-HSA-1428517	Aerobic respiration and respiratory electron transport
R-HSA-1430728	Metabolism

MSigDB gene sets: 235 (showing top): FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN, MODULE_77, MORF_HDAC1, GOBP_ORGANOPHOSPHATE_METABOLIC_PROCESS, MORF_HDAC2, GOBP_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS, CAGCTG_AP4_Q5, GOBP_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS, GOBP_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS, GOBP_MONOATOMIC_CATION_TRANSPORT, GOBP_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS, GOBP_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY, GOBP_ATP_BIOSYNTHETIC_PROCESS, GOBP_OXIDATIVE_PHOSPHORYLATION, GOBP_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS

GO Biological Process (4): mitochondrial electron transport, NADH to ubiquinone (GO:0006120), aerobic respiration (GO:0009060), proton motive force-driven mitochondrial ATP synthesis (GO:0042776), proton transmembrane transport (GO:1902600)

GO Molecular Function (1): NADH dehydrogenase (ubiquinone) activity (GO:0008137)

GO Cellular Component (4): mitochondrion (GO:0005739), mitochondrial inner membrane (GO:0005743), respiratory chain complex I (GO:0045271), membrane (GO:0016020)

Reactome top-level categories

Rollup of top-3 pathways:

Category	Pathways
Aerobic respiration and respiratory electron transport	1
Respiratory electron transport	1
Metabolism	1

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
aerobic electron transport chain	1
mitochondrial ATP synthesis coupled electron transport	1
cellular respiration	1
mitochondrion	1
oxidative phosphorylation	1
proton motive force-driven ATP synthesis	1
monoatomic cation transmembrane transport	1
NADH dehydrogenase activity	1
electron transfer activity	1
proton transmembrane transporter activity	1
oxidoreduction-driven active transmembrane transporter activity	1
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1
active monoatomic ion transmembrane transporter activity	1
cytoplasm	1
intracellular membrane-bounded organelle	1
organelle inner membrane	1
mitochondrial membrane	1
NADH dehydrogenase complex	1
respiratory chain complex	1
transmembrane transporter complex	1
cellular anatomical structure	1

Protein interactions and networks

STRING

944 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
NDUFC1	NDUFB5	O43674	902
NDUFC1	NDUFA5	Q16718	900
NDUFC1	NDUFA2	O43678	881
NDUFC1	NDUFB3	O43676	870
NDUFC1	NDUFV3	P56181	846
NDUFC1	NDUFC2	O95298	836
NDUFC1	NDUFV2	P19404	826
NDUFC1	NDUFA6	P56556	810
NDUFC1	NDUFS6	O75380	798
NDUFC1	NDUFV1	P49821	755
NDUFC1	NDUFS1	P28331	753
NDUFC1	NDUFA7	O95182	722
NDUFC1	NDUFB2	O95178	721
NDUFC1	NDUFA12	Q9UI09	672
NDUFC1	NDUFB6	O95139	660

IntAct

0 interactions, top by confidence:

BioGRID (4): NDUFC1 (Affinity Capture-RNA), NDUFC1 (Negative Genetic), NDUFC1 (Negative Genetic), NDUFC1 (Negative Genetic)

ESM2 similar proteins: A0JMH2, A0PJW6, A5PJW2, B3DI94, B5DFG1, O43677, P0CB69, P0CB70, Q059A4, Q0MQF5, Q0MQF6, Q0V9C9, Q0VCH8, Q13405, Q3SX05, Q3SZA2, Q3SZV6, Q3U6U5, Q4G012, Q4KLZ1, Q4KM93, Q4R5K7, Q4R5Q4, Q4VAE3, Q53S58, Q5EA71, Q5R8X0, Q5XIC2, Q66LN0, Q6DC58, Q6PI78, Q75CX4, Q80YU0, Q863F8, Q863G5, Q8BPE4, Q8BWM0, Q8N159, Q8R4H7, Q95SS8

Diamond homologs: O43677, P0CB69, P0CB70, Q02376, Q0MQF5, Q0MQF6, Q9CQY9

SIGNOR signaling

1 interactions.

A	Effect	B	Mechanism
NDUFC1	“form complex”	“NADH-ubiquinone oxidoreductase-Mitochondrial respiratory chain complex I”	binding

Disease & clinical

Clinical variants and AI predictions

ClinVar

24 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	14
Likely benign	2
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

1738 predictions. Top by Δscore:

Variant	Effect	Δscore
4:139275287:A:AC	donor_gain	1.0000
4:139275288:C:CC	donor_gain	1.0000
4:139275391:TG:T	acceptor_gain	1.0000
4:139275392:GCT:G	acceptor_loss	1.0000
4:139275393:C:CC	acceptor_gain	1.0000
4:139275393:C:T	acceptor_loss	1.0000
4:139292528:A:AC	donor_gain	1.0000
4:139292529:C:CC	donor_gain	1.0000
4:139292529:CTA:C	donor_gain	1.0000
4:139292529:CTACA:C	donor_gain	1.0000
4:139292606:TGAG:T	acceptor_gain	1.0000
4:139292607:GAGCT:G	acceptor_loss	1.0000
4:139292608:AGC:A	acceptor_loss	1.0000
4:139292609:GCTAC:G	acceptor_loss	1.0000
4:139292610:C:CA	acceptor_loss	1.0000
4:139292610:C:CC	acceptor_gain	1.0000
4:139295041:A:AC	donor_gain	1.0000
4:139295042:C:CC	donor_gain	1.0000
4:139295142:TGAAG:T	acceptor_gain	1.0000
4:139295143:GAAG:G	acceptor_gain	1.0000
4:139295144:AAG:A	acceptor_gain	1.0000
4:139295145:AG:A	acceptor_gain	1.0000
4:139295147:C:CC	acceptor_gain	1.0000
4:139301829:TTGGT:T	donor_loss	1.0000
4:139301830:TGG:T	donor_loss	1.0000
4:139301831:GGT:G	donor_loss	1.0000
4:139301832:G:GA	donor_loss	1.0000
4:139301832:G:GG	donor_gain	1.0000
4:139268667:TTTA:T	donor_loss	0.9900
4:139268668:TTACC:T	donor_loss	0.9900

AlphaMissense

471 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
4:139295051:A:G	W55R	0.973
4:139295051:A:T	W55R	0.973
4:139295069:C:G	G49R	0.969
4:139295127:G:C	F29L	0.959
4:139295127:G:T	F29L	0.959
4:139295129:A:G	F29L	0.959
4:139295068:C:T	G49D	0.951
4:139295059:A:T	V52D	0.940
4:139295093:A:G	W41R	0.904
4:139295093:A:T	W41R	0.904
4:139295080:C:T	G45E	0.893
4:139295081:C:G	G45R	0.893
4:139295081:C:T	G45R	0.893
4:139295091:C:A	W41C	0.886
4:139295091:C:G	W41C	0.886
4:139292575:T:G	Y69S	0.885
4:139292608:A:G	L58P	0.867
4:139292565:T:A	R72S	0.862
4:139292565:T:G	R72S	0.862
4:139292572:T:A	K70I	0.862
4:139295049:C:A	W55C	0.862
4:139295049:C:G	W55C	0.862
4:139292576:A:G	Y69H	0.855
4:139292576:A:C	Y69D	0.844
4:139292579:C:T	E68K	0.821
4:139292596:T:G	H62P	0.807
4:139292577:C:A	E68D	0.791
4:139292577:C:G	E68D	0.791
4:139292575:T:C	Y69C	0.789
4:139295083:A:T	V44D	0.780

dbSNP variants (sampled 300 via entrez): RS1000108485 (4:139294808 T>A,C), RS1000124112 (4:139304103 A>G), RS10003164 (4:139296482 C>T), RS1000410436 (4:139302930 T>C), RS1000449463 (4:139301439 A>G), RS1000621992 (4:139290895 G>C), RS1000903599 (4:139296962 C>G,T), RS1000976249 (4:139290740 C>A,T), RS1001512985 (4:139291880 A>G), RS1001554956 (4:139298296 G>A), RS1001683099 (4:139301764 G>A,T), RS1001943175 (4:139303460 A>C,G), RS1002085387 (4:139294048 T>G), RS1002113010 (4:139298075 A>G), RS1002139251 (4:139293767 C>G,T)

Disease associations

OMIM: gene MIM:603844 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: yes

ChEMBL targets (1): CHEMBL2363065 (PROTEIN COMPLEX)

PharmGKB: 1 entry (VIP=true, CPIC=false)

ChEMBL bioactivities

8 potent at pChembl≥5 of 18 total, top 8 by pChembl (potency: 10 = 0.1 nM, 6 = 1 µM).

pChembl	Type	Value	Unit	Molecule
6.06	IC50	870	nM	R-(+)-MARMIN-6’-UNDECANOATE
6.04	IC50	920	nM	R-(+)-MARMIN-6’-LINOLEATE
5.63	IC50	2350	nM	R-(+)-MARMIN-6’-LINOLEATE
5.51	IC50	3080	nM	R-(+)-MARMIN-6’-OCTANOATE
5.43	IC50	3670	nM	R-(+)-MARMIN-6’-UNDECANOATE
5.43	IC50	3710	nM	R-(+)-MARMIN-6’-OCTANOATE
5.31	IC50	4900	nM	(+)-9’-ISOVALEROXYLARICIRESINOL
5.04	IC50	9100	nM	(+)-9’-ISOVALEROXYLARICIRESINOL

PubChem BioAssay actives

8 with measured affinity, of 28 total; 4 most potent distinct compounds. Largely complementary to BindingDB; screening values are coarse (µM, 4 dp), so sub-nM hits tie at the floor.

Compound	Assay	Type	Value	Unit
[(E,3R)-2-hydroxy-2,6-dimethyl-8-(2-oxochromen-7-yl)oxyoct-6-en-3-yl] undecanoate	739270: Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay	ic50	0.8700	uM
[(E,3R)-2-hydroxy-2,6-dimethyl-8-(2-oxochromen-7-yl)oxyoct-6-en-3-yl] (9Z,12Z)-octadeca-9,12-dienoate	739270: Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay	ic50	0.9200	uM
[(E,3R)-2-hydroxy-2,6-dimethyl-8-(2-oxochromen-7-yl)oxyoct-6-en-3-yl] octanoate	739270: Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay	ic50	3.0800	uM
[(2S,3R,4R)-2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-3-yl]methyl 3-methylbutanoate	739269: Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay	ic50	4.9000	uM

CTD chemical–gene interactions

40 total (human), top 30 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
bisphenol A	affects expression, decreases expression, increases expression	3
Acetaminophen	decreases expression, affects cotreatment	2
Air Pollutants	increases expression, affects expression, affects cotreatment, increases abundance	2
Ozone	affects cotreatment, increases expression, increases abundance, affects expression	2
alpha-pinene	affects cotreatment, increases expression, increases abundance	1
sodium arsenite	increases expression	1
ochratoxin A	increases expression	1
methacrylaldehyde	affects cotreatment, increases expression, increases abundance	1
perfluorooctane sulfonic acid	decreases expression	1
CGP 52608	affects binding, increases reaction	1
corosolic acid	decreases expression	1
K 7174	decreases expression	1
nutlin 3	affects cotreatment, increases expression	1
Acrolein	affects cotreatment, increases expression, increases abundance	1
Vehicle Emissions	increases expression, increases abundance	1
Camptothecin	increases expression	1
Carmustine	decreases expression	1
Dactinomycin	affects cotreatment, increases expression	1
Dietary Carbohydrates	increases expression	1
Doxorubicin	increases expression	1
Estradiol	decreases expression	1
Fluorouracil	affects expression	1
Lipopolysaccharides	affects cotreatment, decreases expression	1
Nickel	decreases expression	1
Niclosamide	increases expression	1
Tetrachlorodibenzodioxin	decreases expression	1
Tretinoin	increases expression	1
Tunicamycin	decreases expression	1
Urethane	decreases expression	1
Valproic Acid	increases expression	1

ChEMBL screening assays

4 unique, capped per target: 4 binding

Representative assays (with source publication via chembl_document):

Assay ID	Type	Description	Source paper
CHEMBL2353025	Binding	Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation at 30 uM incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay	Semisynthetic studies identify mitochondria poisons from botanical dietary supplements–geranyloxycoumarins from Aegle marmelos. — Bioorg Med Chem

Cellosaurus cell lines

1 cell lines: 1 transformed cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_B3C5	Abcam HEK293T NDUFC1 KO	Transformed cell line	Female

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.