NECTIN1-AS1

Summary

NECTIN1-AS1 (NECTIN1 antisense RNA 1, HGNC:54270) is a long non-coding RNA gene on chromosome 11q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54270
Approved symbol	NECTIN1-AS1
Name	NECTIN1 antisense RNA 1
Location	11q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255247
Ensembl biotype	lncRNA
Entrez	105369525
RNAcentral	URS000036F84F — lncRNA, 559 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000529229

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000529229 — 3 exons

Exon	Start	End
ENSE00002144311	119713599	119713925
ENSE00002156395	119712892	119713012
ENSE00002173284	119709920	119710030

Expression profiles

Bgee: expression breadth broad, 90 present calls, max score 74.15.

Top tissues by expression

90 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	74.15	silver quality
uterine cervix	UBERON:0000002	69.85	gold quality
colonic epithelium	UBERON:0000397	65.51	silver quality
tonsil	UBERON:0002372	65.28	gold quality
liver	UBERON:0002107	62.88	gold quality
urinary bladder	UBERON:0001255	61.66	gold quality
bone marrow	UBERON:0002371	59.89	gold quality
monocyte	CL:0000576	58.74	gold quality
skin of abdomen	UBERON:0001416	57.81	gold quality
ectocervix	UBERON:0012249	56.74	gold quality
right testis	UBERON:0004534	56.50	gold quality
testis	UBERON:0000473	55.88	gold quality
left testis	UBERON:0004533	55.60	gold quality
vagina	UBERON:0000996	54.99	gold quality
zone of skin	UBERON:0000014	54.78	gold quality
duodenum	UBERON:0002114	53.68	gold quality
prefrontal cortex	UBERON:0000451	53.51	gold quality
islet of Langerhans	UBERON:0000006	52.37	gold quality
blood	UBERON:0000178	52.18	silver quality
skin of leg	UBERON:0001511	51.80	gold quality
esophagus	UBERON:0001043	51.79	gold quality
esophagus mucosa	UBERON:0002469	51.73	gold quality
corpus callosum	UBERON:0002336	51.19	silver quality
multicellular organism	UBERON:0000468	50.85	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.85	gold quality
kidney	UBERON:0002113	50.41	silver quality
muscle of leg	UBERON:0001383	49.81	gold quality
superior frontal gyrus	UBERON:0002661	49.44	gold quality
pancreas	UBERON:0001264	48.91	gold quality
minor salivary gland	UBERON:0001830	48.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.