NECTIN1-DT

Summary

NECTIN1-DT (NECTIN1 divergent transcript, HGNC:55513) is a long non-coding RNA gene on chromosome 11q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55513
Approved symbol	NECTIN1-DT
Name	NECTIN1 divergent transcript
Location	11q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254854
Ensembl biotype	lncRNA
Entrez	102724301
RNAcentral	URS00002DADD2 — lncRNA, 523 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 58 — 58 lncRNA

ENST00000533253, ENST00000814204, ENST00000814205, ENST00000814206, ENST00000814207, ENST00000814208, ENST00000814209, ENST00000814210, ENST00000814211, ENST00000814212, ENST00000814213, ENST00000814214, ENST00000814215, ENST00000814216, ENST00000814217, ENST00000814218, ENST00000814219, ENST00000814220, ENST00000814221, ENST00000814222, ENST00000814223, ENST00000814224, ENST00000814225, ENST00000814226, ENST00000814227, ENST00000814228, ENST00000814229, ENST00000814230, ENST00000814231, ENST00000814232, ENST00000814233, ENST00000814234, ENST00000814235, ENST00000814236, ENST00000814237, ENST00000814238, ENST00000814239, ENST00000814240, ENST00000814241, ENST00000814242, ENST00000814243, ENST00000814244, ENST00000814245, ENST00000814246, ENST00000814247, ENST00000814248, ENST00000814249, ENST00000814250, ENST00000814251, ENST00000814252, ENST00000814253, ENST00000814254, ENST00000814255, ENST00000814256, ENST00000814257, ENST00000814258, ENST00000814259, ENST00000814260

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000533253 — 6 exons

Exon	Start	End
ENSE00002164745	119736807	119736918
ENSE00002180817	119733657	119733750
ENSE00004215045	119821440	119821591
ENSE00004215046	119821670	119822143
ENSE00004215076	119729578	119729806
ENSE00004215084	119739531	119739788

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 93.78.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	93.78	gold quality
bone marrow cell	CL:0002092	72.37	silver quality
body of pancreas	UBERON:0001150	71.24	gold quality
lower esophagus mucosa	UBERON:0035834	70.64	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.50	gold quality
Ammon’s horn	UBERON:0001954	69.97	gold quality
colonic epithelium	UBERON:0000397	68.66	silver quality
anterior cingulate cortex	UBERON:0009835	68.01	gold quality
pancreas	UBERON:0001264	67.76	gold quality
mucosa of transverse colon	UBERON:0004991	67.72	gold quality
ganglionic eminence	UBERON:0004023	67.55	gold quality
cerebral cortex	UBERON:0000956	66.87	gold quality
bone marrow	UBERON:0002371	66.80	gold quality
rectum	UBERON:0001052	66.69	gold quality
prefrontal cortex	UBERON:0000451	66.66	gold quality
esophagus mucosa	UBERON:0002469	66.45	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	66.37	gold quality
amygdala	UBERON:0001876	66.36	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.25	gold quality
frontal cortex	UBERON:0001870	66.02	gold quality
right frontal lobe	UBERON:0002810	65.84	gold quality
substantia nigra	UBERON:0002038	65.79	gold quality
hypothalamus	UBERON:0001898	62.77	gold quality
brain	UBERON:0000955	62.42	gold quality
putamen	UBERON:0001874	61.82	gold quality
skin of abdomen	UBERON:0001416	61.60	gold quality
adenohypophysis	UBERON:0002196	61.49	gold quality
cortical plate	UBERON:0005343	61.43	gold quality
pituitary gland	UBERON:0000007	61.22	gold quality
duodenum	UBERON:0002114	60.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.