NECTIN3-AS1

Summary

NECTIN3-AS1 (NECTIN3 antisense RNA 1, HGNC:40813) is a long non-coding RNA gene on chromosome 3q13.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40813
Approved symbol	NECTIN3-AS1
Name	NECTIN3 antisense RNA 1
Location	3q13.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000242242
Ensembl biotype	lncRNA
Entrez	100506555
RNAcentral	URS000075AD49 — lncRNA, 1142 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 47 — 47 lncRNA

ENST00000383686, ENST00000463025, ENST00000467426, ENST00000474769, ENST00000476301, ENST00000485473, ENST00000491709, ENST00000690584, ENST00000690883, ENST00000691789, ENST00000803769, ENST00000803770, ENST00000803771, ENST00000803772, ENST00000803773, ENST00000803774, ENST00000803775, ENST00000803776, ENST00000803777, ENST00000803778, ENST00000803779, ENST00000803780, ENST00000803781, ENST00000803782, ENST00000803783, ENST00000803784, ENST00000803785, ENST00000803786, ENST00000803787, ENST00000803788, ENST00000803789, ENST00000803790, ENST00000803791, ENST00000803792, ENST00000803793, ENST00000803794, ENST00000803795, ENST00000803796, ENST00000803797, ENST00000803798, ENST00000803799, ENST00000803800, ENST00000803801, ENST00000803802, ENST00000803803, ENST00000803804, ENST00000803805

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000383686 — 4 exons

Exon	Start	End
ENSE00001498104	110892123	110892603
ENSE00001927784	111069264	111069471
ENSE00001947310	110893138	110893830
ENSE00004194601	111070878	111071411

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 85.58.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3808 / max 54.2742, expressed in 158 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
43713	0.3313	139
43712	0.0495	21

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	85.58	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.05	gold quality
left testis	UBERON:0004533	84.88	gold quality
sperm	CL:0000019	84.13	silver quality
testis	UBERON:0000473	82.24	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.45	gold quality
buccal mucosa cell	CL:0002336	80.09	gold quality
bone marrow cell	CL:0002092	78.50	gold quality
kidney epithelium	UBERON:0004819	75.14	gold quality
cortical plate	UBERON:0005343	72.97	gold quality
prefrontal cortex	UBERON:0000451	71.23	gold quality
cerebellar vermis	UBERON:0004720	71.11	gold quality
islet of Langerhans	UBERON:0000006	70.61	gold quality
calcaneal tendon	UBERON:0003701	68.73	gold quality
left ventricle myocardium	UBERON:0006566	68.45	gold quality
cardiac muscle of right atrium	UBERON:0003379	67.74	gold quality
upper arm skin	UBERON:0004263	67.72	gold quality
frontal cortex	UBERON:0001870	67.44	gold quality
right frontal lobe	UBERON:0002810	67.35	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.21	gold quality
neocortex	UBERON:0001950	67.20	gold quality
anterior cingulate cortex	UBERON:0009835	67.02	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	66.48	gold quality
ventricular zone	UBERON:0003053	65.13	gold quality
cerebral cortex	UBERON:0000956	64.89	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	64.11	gold quality
myocardium	UBERON:0002349	64.10	gold quality
parotid gland	UBERON:0001831	63.86	gold quality
ganglionic eminence	UBERON:0004023	63.86	gold quality
skeletal muscle tissue	UBERON:0001134	63.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.43

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.