NECTIN4-AS1

Summary

NECTIN4-AS1 (NECTIN4 antisense RNA 1, HGNC:40893) is a long non-coding RNA gene on chromosome 1q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40893
Approved symbol	NECTIN4-AS1
Name	NECTIN4 antisense RNA 1
Location	1q23.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL591806.1
Ensembl gene	ENSG00000228917
Ensembl biotype	lncRNA
Entrez	105371471
RNAcentral	URS00026A2841 — lncRNA, 4909 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000447167, ENST00000778854, ENST00000778855, ENST00000778856, ENST00000778857, ENST00000778858, ENST00000778859, ENST00000778860

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000447167 — 3 exons

Exon	Start	End
ENSE00001591408	161084937	161085028
ENSE00001641975	161084465	161084812
ENSE00001730538	161086903	161087571

Expression profiles

Bgee: expression breadth broad, 52 present calls, max score 68.81.

Top tissues by expression

52 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	68.81	silver quality
colonic epithelium	UBERON:0000397	66.92	silver quality
placenta	UBERON:0001987	65.53	gold quality
uterine cervix	UBERON:0000002	63.92	gold quality
left ovary	UBERON:0002119	55.53	gold quality
myometrium	UBERON:0001296	53.30	gold quality
skin of abdomen	UBERON:0001416	52.86	gold quality
esophagus	UBERON:0001043	51.47	gold quality
zone of skin	UBERON:0000014	51.25	gold quality
monocyte	CL:0000576	50.89	silver quality
esophagus mucosa	UBERON:0002469	50.85	gold quality
urinary bladder	UBERON:0001255	50.25	gold quality
multicellular organism	UBERON:0000468	49.95	gold quality
skin of leg	UBERON:0001511	49.50	gold quality
ectocervix	UBERON:0012249	49.27	gold quality
gall bladder	UBERON:0002110	48.99	gold quality
ovary	UBERON:0000992	48.78	gold quality
adult mammalian kidney	UBERON:0000082	48.76	gold quality
vagina	UBERON:0000996	48.73	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.54	gold quality
tonsil	UBERON:0002372	48.17	silver quality
lower esophagus mucosa	UBERON:0035834	47.87	gold quality
gastrocnemius	UBERON:0001388	47.09	silver quality
islet of Langerhans	UBERON:0000006	46.93	gold quality
subcutaneous adipose tissue	UBERON:0002190	46.28	gold quality
prostate gland	UBERON:0002367	46.11	gold quality
tibial nerve	UBERON:0001323	45.50	gold quality
blood	UBERON:0000178	45.32	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	45.14	gold quality
colon	UBERON:0001155	44.69	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.90

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.