NEDD4L-AS1

Summary

NEDD4L-AS1 (NEDD4L antisense RNA 1, HGNC:58681) is a long non-coding RNA gene on chromosome 18q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58681
Approved symbol	NEDD4L-AS1
Name	NEDD4L antisense RNA 1
Location	18q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267396
Ensembl biotype	lncRNA
Entrez	142876908

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000590318, ENST00000721363, ENST00000721364, ENST00000721365, ENST00000721366

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000590318 — 2 exons

Exon	Start	End
ENSE00004040977	58399997	58400099
ENSE00004040980	58398602	58399344

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 93.05.

Top tissues by expression

205 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.05	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	91.40	gold quality
pancreatic ductal cell	CL:0002079	76.47	silver quality
colonic epithelium	UBERON:0000397	75.17	gold quality
upper arm skin	UBERON:0004263	73.64	gold quality
cortical plate	UBERON:0005343	72.80	gold quality
anterior cingulate cortex	UBERON:0009835	72.71	gold quality
nasal cavity epithelium	UBERON:0005384	71.36	gold quality
ganglionic eminence	UBERON:0004023	71.11	gold quality
epithelial cell of pancreas	CL:0000083	70.93	gold quality
myocardium	UBERON:0002349	68.36	gold quality
muscle of leg	UBERON:0001383	68.11	gold quality
right atrium auricular region	UBERON:0006631	68.09	gold quality
gastrocnemius	UBERON:0001388	67.78	gold quality
tibialis anterior	UBERON:0001385	67.75	silver quality
medial globus pallidus	UBERON:0002477	67.48	silver quality
metanephros	UBERON:0000081	67.45	gold quality
ileal mucosa	UBERON:0000331	66.41	silver quality
cardiac muscle of right atrium	UBERON:0003379	66.25	gold quality
left ventricle myocardium	UBERON:0006566	66.18	gold quality
prefrontal cortex	UBERON:0000451	66.14	gold quality
body of stomach	UBERON:0001161	65.10	gold quality
globus pallidus	UBERON:0001875	65.06	silver quality
cerebellar hemisphere	UBERON:0002245	64.77	gold quality
kidney epithelium	UBERON:0004819	64.72	gold quality
right frontal lobe	UBERON:0002810	64.39	gold quality
esophagus squamous epithelium	UBERON:0006920	63.90	gold quality
lateral globus pallidus	UBERON:0002476	63.12	silver quality
nucleus accumbens	UBERON:0001882	63.11	gold quality
tendon	UBERON:0000043	62.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.