NEGR1-IT1

Summary

NEGR1-IT1 (NEGR1 intronic transcript 1, HGNC:41432) is a long non-coding RNA gene on chromosome 1p31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41432
Approved symbol	NEGR1-IT1
Name	NEGR1 intronic transcript 1
Location	1p31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228853
Ensembl biotype	lncRNA
Entrez	100852409
RNAcentral	URS000075C659 — lncRNA, 554 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000453121

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453121 — 3 exons

Exon	Start	End
ENSE00001629939	71836980	71837012
ENSE00001730582	71794232	71794536
ENSE00001770800	71798075	71798270

Expression profiles

Bgee: expression breadth broad, 59 present calls, max score 87.63.

Top tissues by expression

163 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	87.63	gold quality
upper leg skin	UBERON:0004262	60.17	gold quality
monocyte	CL:0000576	59.26	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	59.12	gold quality
calcaneal tendon	UBERON:0003701	57.91	gold quality
tendon	UBERON:0000043	51.98	silver quality
adrenal tissue	UBERON:0018303	50.70	silver quality
tibial artery	UBERON:0007610	47.65	gold quality
prefrontal cortex	UBERON:0000451	47.22	gold quality
tendon of biceps brachii	UBERON:0008188	47.05	gold quality
gastrocnemius	UBERON:0001388	46.36	silver quality
corpus callosum	UBERON:0002336	45.47	silver quality
aorta	UBERON:0000947	45.39	silver quality
adult mammalian kidney	UBERON:0000082	44.55	silver quality
body of pancreas	UBERON:0001150	44.40	silver quality
right atrium auricular region	UBERON:0006631	44.36	gold quality
heart left ventricle	UBERON:0002084	44.27	silver quality
lower lobe of lung	UBERON:0008949	43.86	silver quality
skin of hip	UBERON:0001554	43.54	silver quality
fundus of stomach	UBERON:0001160	43.51	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
heart	UBERON:0000948	43.35	silver quality
cardiac ventricle	UBERON:0002082	43.10	silver quality
testis	UBERON:0000473	43.08	silver quality
anterior cingulate cortex	UBERON:0009835	43.03	silver quality
stomach	UBERON:0000945	43.02	silver quality
left coronary artery	UBERON:0001626	42.93	silver quality
Brodmann (1909) area 9	UBERON:0013540	42.71	gold quality
cardiac atrium	UBERON:0002081	42.67	gold quality
secondary oocyte	CL:0000655	42.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.