NEUROG2-AS1

Summary

NEUROG2-AS1 (NEUROG2 and ZGRF1 antisense RNA 1, HGNC:40656) is a long non-coding RNA gene on chromosome 4q25.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40656
Approved symbol	NEUROG2-AS1
Name	NEUROG2 and ZGRF1 antisense RNA 1
Location	4q25
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249509
Ensembl biotype	lncRNA
Entrez	105377372
RNAcentral	URS0000E60A14 — lncRNA, 613 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 44 — 44 lncRNA

ENST00000504009, ENST00000506057, ENST00000754766, ENST00000754767, ENST00000754768, ENST00000754769, ENST00000754770, ENST00000754771, ENST00000754772, ENST00000754773, ENST00000754774, ENST00000754775, ENST00000754776, ENST00000754777, ENST00000754778, ENST00000754779, ENST00000754780, ENST00000754781, ENST00000754782, ENST00000754783, ENST00000754784, ENST00000754785, ENST00000754786, ENST00000754787, ENST00000754788, ENST00000754789, ENST00000754790, ENST00000754791, ENST00000754792, ENST00000754793, ENST00000754794, ENST00000754795, ENST00000754796, ENST00000754797, ENST00000754798, ENST00000754799, ENST00000754800, ENST00000754801, ENST00000754802, ENST00000754803, ENST00000754804, ENST00000754805, ENST00000754806, ENST00000754807

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504009 — 4 exons

Exon	Start	End
ENSE00002040686	112525259	112525309
ENSE00002515231	112530382	112530500
ENSE00004103118	112515350	112515640
ENSE00004103125	112546785	112546888

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 87.21.

Top tissues by expression

107 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.21	gold quality
cortical plate	UBERON:0005343	86.46	gold quality
thymus	UBERON:0002370	84.14	silver quality
ganglionic eminence	UBERON:0004023	75.92	gold quality
ventricular zone	UBERON:0003053	71.25	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
Ammon’s horn	UBERON:0001954	68.13	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
lymph node	UBERON:0000029	65.53	gold quality
right testis	UBERON:0004534	63.86	gold quality
left testis	UBERON:0004533	63.68	gold quality
testis	UBERON:0000473	63.27	gold quality
skeletal muscle tissue	UBERON:0001134	62.55	gold quality
calcaneal tendon	UBERON:0003701	62.31	gold quality
monocyte	CL:0000576	60.23	gold quality
prefrontal cortex	UBERON:0000451	59.73	gold quality
cerebellum	UBERON:0002037	57.56	gold quality
cerebellar cortex	UBERON:0002129	57.56	gold quality
bone marrow	UBERON:0002371	57.40	silver quality
cerebellar hemisphere	UBERON:0002245	57.33	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.31	gold quality
anterior cingulate cortex	UBERON:0009835	57.26	gold quality
cerebral cortex	UBERON:0000956	56.98	gold quality
amygdala	UBERON:0001876	56.25	gold quality
putamen	UBERON:0001874	55.44	gold quality
brain	UBERON:0000955	54.88	gold quality
frontal cortex	UBERON:0001870	54.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	53.56	gold quality
Brodmann (1909) area 9	UBERON:0013540	53.17	gold quality
superior frontal gyrus	UBERON:0002661	52.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.