NFE2L1-DT

Summary

NFE2L1-DT (NFE2L1 divergent transcript, HGNC:54812) is a long non-coding RNA gene on chromosome 17q21.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54812
Approved symbol	NFE2L1-DT
Name	NFE2L1 divergent transcript
Location	17q21.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263412
Ensembl biotype	lncRNA
Entrez	116435298
RNAcentral	URS0002123158 — lncRNA, 519 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 31 — 30 lncRNA, 1 retained_intron

ENST00000578660, ENST00000584428, ENST00000805742, ENST00000805743, ENST00000805744, ENST00000805745, ENST00000805746, ENST00000805747, ENST00000805748, ENST00000805749, ENST00000805750, ENST00000805751, ENST00000805752, ENST00000805753, ENST00000805754, ENST00000805755, ENST00000805756, ENST00000805757, ENST00000805758, ENST00000805759, ENST00000805760, ENST00000805761, ENST00000805762, ENST00000805763, ENST00000805764, ENST00000805765, ENST00000805766, ENST00000805767, ENST00000805768, ENST00000805769, ENST00000805770

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578660 — 1 exons

Exon	Start	End
ENSE00004198260	48045141	48048604

Expression profiles

Bgee: expression breadth ubiquitous, 154 present calls, max score 86.87.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1033 / max 29.7578, expressed in 526 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
166626	1.0869	520
166625	0.0164	4

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.55	gold quality
gastrocnemius	UBERON:0001388	68.62	gold quality
colonic epithelium	UBERON:0000397	67.98	silver quality
muscle of leg	UBERON:0001383	67.98	gold quality
cortical plate	UBERON:0005343	67.11	gold quality
right uterine tube	UBERON:0001302	66.01	gold quality
sural nerve	UBERON:0015488	65.51	silver quality
buccal mucosa cell	CL:0002336	63.98	gold quality
stromal cell of endometrium	CL:0002255	63.66	gold quality
left testis	UBERON:0004533	63.15	gold quality
ventricular zone	UBERON:0003053	63.13	gold quality
right testis	UBERON:0004534	62.53	gold quality
ganglionic eminence	UBERON:0004023	62.50	gold quality
right lobe of thyroid gland	UBERON:0001119	62.06	gold quality
right coronary artery	UBERON:0001625	61.90	gold quality
testis	UBERON:0000473	61.73	gold quality
apex of heart	UBERON:0002098	61.31	gold quality
mucosa of transverse colon	UBERON:0004991	60.93	gold quality
thyroid gland	UBERON:0002046	60.31	gold quality
left lobe of thyroid gland	UBERON:0001120	60.11	gold quality
left adrenal gland cortex	UBERON:0035825	58.55	gold quality
metanephros cortex	UBERON:0010533	58.33	gold quality
left adrenal gland	UBERON:0001234	58.23	gold quality
secondary oocyte	CL:0000655	58.15	gold quality
lower esophagus muscularis layer	UBERON:0035833	58.10	gold quality
lower esophagus	UBERON:0013473	58.03	gold quality
ascending aorta	UBERON:0001496	57.77	gold quality
body of uterus	UBERON:0009853	57.77	gold quality
thoracic aorta	UBERON:0001515	57.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.