NFIB-AS1

Summary

NFIB-AS1 (NFIB antisense RNA 1, HGNC:56058) is a long non-coding RNA gene on chromosome 9p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56058
Approved symbol	NFIB-AS1
Name	NFIB antisense RNA 1
Location	9p22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL136366.1
Ensembl gene	ENSG00000225472
Ensembl biotype	lncRNA
Entrez	123706550
RNAcentral	URS00026A1ED4 — lncRNA, 1672 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000416996, ENST00000440947, ENST00000659981, ENST00000671131, ENST00000842090, ENST00000842091, ENST00000842092, ENST00000842093

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416996 — 2 exons

Exon	Start	End
ENSE00001687217	14357152	14357854
ENSE00001767010	14317085	14317345

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 88.77.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ventricular zone	UBERON:0003053	88.77	gold quality
ganglionic eminence	UBERON:0004023	88.65	gold quality
cortical plate	UBERON:0005343	79.82	gold quality
right coronary artery	UBERON:0001625	76.60	gold quality
amygdala	UBERON:0001876	76.60	gold quality
temporal lobe	UBERON:0001871	76.39	gold quality
descending thoracic aorta	UBERON:0002345	75.67	gold quality
caudate nucleus	UBERON:0001873	74.67	gold quality
putamen	UBERON:0001874	74.01	gold quality
nucleus accumbens	UBERON:0001882	73.74	gold quality
thoracic aorta	UBERON:0001515	72.74	gold quality
left coronary artery	UBERON:0001626	72.67	gold quality
Ammon’s horn	UBERON:0001954	72.67	gold quality
ascending aorta	UBERON:0001496	72.57	gold quality
anterior cingulate cortex	UBERON:0009835	72.33	gold quality
popliteal artery	UBERON:0002250	71.39	gold quality
tibial artery	UBERON:0007610	71.39	gold quality
hypothalamus	UBERON:0001898	70.73	gold quality
cerebral cortex	UBERON:0000956	70.66	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.30	gold quality
heart left ventricle	UBERON:0002084	70.01	gold quality
prefrontal cortex	UBERON:0000451	69.98	gold quality
brain	UBERON:0000955	69.88	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.69	gold quality
cerebellar hemisphere	UBERON:0002245	69.65	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.65	gold quality
cerebellar cortex	UBERON:0002129	69.61	gold quality
frontal cortex	UBERON:0001870	69.54	gold quality
cerebellum	UBERON:0002037	69.54	gold quality
right frontal lobe	UBERON:0002810	69.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.