NFIX-AS1

Summary

NFIX-AS1 (NFIX antisense RNA 1, HGNC:58573) is a long non-coding RNA gene on chromosome 19p13.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58573
Approved symbol	NFIX-AS1
Name	NFIX antisense RNA 1
Location	19p13.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267417
Ensembl biotype	lncRNA
Entrez	107985286

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000586630, ENST00000796022, ENST00000796023

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000586630 — 2 exons

Exon	Start	End
ENSE00004181218	13014206	13014511
ENSE00004181219	13013655	13013878

Expression profiles

Bgee: expression breadth ubiquitous, 107 present calls, max score 83.98.

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	83.98	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.24	gold quality
muscle of leg	UBERON:0001383	71.78	gold quality
skeletal muscle tissue	UBERON:0001134	71.67	gold quality
bone marrow cell	CL:0002092	70.97	silver quality
gastrocnemius	UBERON:0001388	70.81	gold quality
thymus	UBERON:0002370	68.38	silver quality
ganglionic eminence	UBERON:0004023	66.44	gold quality
cerebellar vermis	UBERON:0004720	64.61	gold quality
bone marrow	UBERON:0002371	64.00	gold quality
tonsil	UBERON:0002372	62.69	silver quality
calcaneal tendon	UBERON:0003701	62.18	gold quality
right hemisphere of cerebellum	UBERON:0014890	60.70	gold quality
cerebellar hemisphere	UBERON:0002245	60.50	gold quality
cerebellar cortex	UBERON:0002129	60.44	gold quality
cerebellum	UBERON:0002037	60.38	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.64	gold quality
prefrontal cortex	UBERON:0000451	56.77	gold quality
descending thoracic aorta	UBERON:0002345	55.97	gold quality
monocyte	CL:0000576	54.79	gold quality
duodenum	UBERON:0002114	54.16	gold quality
ascending aorta	UBERON:0001496	53.66	gold quality
substantia nigra	UBERON:0002038	53.52	gold quality
thoracic aorta	UBERON:0001515	53.32	gold quality
blood	UBERON:0000178	53.30	gold quality
saliva-secreting gland	UBERON:0001044	53.24	gold quality
putamen	UBERON:0001874	53.21	gold quality
prostate gland	UBERON:0002367	52.91	gold quality
gall bladder	UBERON:0002110	52.48	gold quality
brain	UBERON:0000955	52.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.