NFKB1-AS1

Summary

NFKB1-AS1 (NFKB1 antisense RNA 1, HGNC:58149) is a long non-coding RNA gene.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58149
Approved symbol	NFKB1-AS1
Name	NFKB1 antisense RNA 1
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-499E18.1
Ensembl gene	ENSG00000248161
Ensembl biotype	lncRNA
Entrez	105377621
RNAcentral	URS0000A76F22 — lncRNA, 766 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000502883, ENST00000505709, ENST00000506972, ENST00000512915, ENST00000843825

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502883 — 3 exons

Exon	Start	End
ENSE00002028515	102431062	102431249
ENSE00002031333	102418602	102418988
ENSE00002448903	102419697	102419794

Expression profiles

Bgee: expression breadth ubiquitous, 178 present calls, max score 87.33.

Top tissues by expression

276 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.33	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.50	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	77.95	gold quality
mucosa of transverse colon	UBERON:0004991	76.17	gold quality
right uterine tube	UBERON:0001302	75.39	gold quality
spinal cord	UBERON:0002240	75.22	gold quality
ventricular zone	UBERON:0003053	73.88	gold quality
stromal cell of endometrium	CL:0002255	72.85	gold quality
anterior cingulate cortex	UBERON:0009835	72.41	gold quality
cingulate cortex	UBERON:0003027	72.35	gold quality
cranial nerve II	UBERON:0000941	72.02	gold quality
ganglionic eminence	UBERON:0004023	71.87	gold quality
right frontal lobe	UBERON:0002810	71.61	gold quality
caudate nucleus	UBERON:0001873	71.51	gold quality
Brodmann (1909) area 9	UBERON:0013540	71.09	gold quality
prefrontal cortex	UBERON:0000451	70.84	gold quality
nucleus accumbens	UBERON:0001882	70.82	gold quality
hypothalamus	UBERON:0001898	70.57	gold quality
putamen	UBERON:0001874	70.18	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	70.04	gold quality
right lung	UBERON:0002167	70.03	gold quality
omental fat pad	UBERON:0010414	69.58	gold quality
body of uterus	UBERON:0009853	69.57	gold quality
cortical plate	UBERON:0005343	69.56	gold quality
peritoneum	UBERON:0002358	69.50	gold quality
amygdala	UBERON:0001876	69.30	gold quality
cerebellar hemisphere	UBERON:0002245	69.26	gold quality
cerebellar cortex	UBERON:0002129	69.20	gold quality
germinal epithelium of ovary	UBERON:0001304	68.95	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	68.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.