NFYC-AS1

Summary

NFYC-AS1 (NFYC antisense RNA 1, HGNC:49451) is a long non-coding RNA gene on chromosome 1p34.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49451
Approved symbol	NFYC-AS1
Name	NFYC antisense RNA 1
Location	1p34.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	0808y08y
Ensembl gene	ENSG00000272145
Ensembl biotype	lncRNA
Entrez	100130557
RNAcentral	URS000075DDC4 — lncRNA, 3182 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000440100, ENST00000606277, ENST00000768693, ENST00000768775

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440100 — 5 exons

Exon	Start	End
ENSE00001717528	40681495	40681550
ENSE00001729609	40673316	40673458
ENSE00001735638	40669089	40669115
ENSE00001743881	40669427	40669607
ENSE00001788535	40687525	40687588

Expression profiles

Bgee: expression breadth ubiquitous, 166 present calls, max score 84.49.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.8290 / max 104.1237, expressed in 1414 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
11934	4.1474	1361
11933	0.6816	351

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.49	gold quality
buccal mucosa cell	CL:0002336	81.41	silver quality
metanephros cortex	UBERON:0010533	75.61	gold quality
gastrocnemius	UBERON:0001388	74.16	gold quality
muscle of leg	UBERON:0001383	73.61	gold quality
right hemisphere of cerebellum	UBERON:0014890	73.07	gold quality
body of uterus	UBERON:0009853	73.05	gold quality
cerebellar hemisphere	UBERON:0002245	73.04	gold quality
cerebellar cortex	UBERON:0002129	72.99	gold quality
colonic epithelium	UBERON:0000397	72.71	silver quality
right uterine tube	UBERON:0001302	72.40	gold quality
apex of heart	UBERON:0002098	71.88	gold quality
right ovary	UBERON:0002118	71.74	gold quality
lower esophagus muscularis layer	UBERON:0035833	71.73	gold quality
lower esophagus	UBERON:0013473	71.71	gold quality
muscle layer of sigmoid colon	UBERON:0035805	71.55	gold quality
right coronary artery	UBERON:0001625	71.38	gold quality
left ovary	UBERON:0002119	71.35	gold quality
right lobe of thyroid gland	UBERON:0001119	71.09	gold quality
left lobe of thyroid gland	UBERON:0001120	71.02	gold quality
cerebellum	UBERON:0002037	71.02	gold quality
vermiform appendix	UBERON:0001154	70.82	gold quality
minor salivary gland	UBERON:0001830	70.64	gold quality
endocervix	UBERON:0000458	70.18	gold quality
bone marrow cell	CL:0002092	70.16	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	70.01	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	69.95	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.93	gold quality
transverse colon	UBERON:0001157	69.84	gold quality
small intestine Peyer’s patch	UBERON:0003454	69.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.51

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.