NGF-AS1

Summary

NGF-AS1 (NGF antisense RNA 1, HGNC:53922) is a long non-coding RNA gene on chromosome 1p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53922
Approved symbol	NGF-AS1
Name	NGF antisense RNA 1
Location	1p13.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP4-663N10.1
Ensembl gene	ENSG00000228035
Ensembl biotype	lncRNA
Entrez	112840934
RNAcentral	URS0000049FC4 — lncRNA, 2610 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000425449, ENST00000793538, ENST00000793539, ENST00000793540, ENST00000793541, ENST00000793542, ENST00000793543, ENST00000793544, ENST00000793545, ENST00000793546

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425449 — 2 exons

Exon	Start	End
ENSE00001698081	115365670	115368072
ENSE00001728145	115283034	115283240

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 61.79.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
descending thoracic aorta	UBERON:0002345	61.79	gold quality
thoracic aorta	UBERON:0001515	58.29	gold quality
left coronary artery	UBERON:0001626	58.14	gold quality
ascending aorta	UBERON:0001496	57.94	gold quality
popliteal artery	UBERON:0002250	57.62	gold quality
tibial artery	UBERON:0007610	57.62	gold quality
subcutaneous adipose tissue	UBERON:0002190	56.85	gold quality
cortical plate	UBERON:0005343	56.69	gold quality
adipose tissue	UBERON:0001013	56.60	gold quality
omental fat pad	UBERON:0010414	55.82	gold quality
right atrium auricular region	UBERON:0006631	55.48	gold quality
heart	UBERON:0000948	52.64	gold quality
skeletal muscle tissue	UBERON:0001134	52.22	silver quality
thoracic mammary gland	UBERON:0005200	52.22	gold quality
tibial nerve	UBERON:0001323	52.09	gold quality
lymph node	UBERON:0000029	51.80	gold quality
multicellular organism	UBERON:0000468	51.41	gold quality
fundus of stomach	UBERON:0001160	50.70	gold quality
calcaneal tendon	UBERON:0003701	50.63	silver quality
right lobe of thyroid gland	UBERON:0001119	50.58	gold quality
mucosa of stomach	UBERON:0001199	50.56	gold quality
monocyte	CL:0000576	49.49	silver quality
islet of Langerhans	UBERON:0000006	49.45	gold quality
right ovary	UBERON:0002118	49.12	gold quality
prefrontal cortex	UBERON:0000451	48.93	silver quality
vermiform appendix	UBERON:0001154	48.87	gold quality
endometrium	UBERON:0001295	48.77	gold quality
pancreas	UBERON:0001264	48.47	gold quality
small intestine Peyer’s patch	UBERON:0003454	48.31	gold quality
left lobe of thyroid gland	UBERON:0001120	48.24	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.94

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.