NHS-AS1

Summary

NHS-AS1 (NHS antisense RNA 1, HGNC:40403) is a long non-coding RNA gene on chromosome Xp22.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40403
Approved symbol	NHS-AS1
Name	NHS antisense RNA 1
Location	Xp22.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230020
Ensembl biotype	lncRNA
Entrez	100873920
RNAcentral	URS000075DB40 — lncRNA, 383 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000452788

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000452788 — 2 exons

Exon	Start	End
ENSE00001726194	17552349	17552524
ENSE00001795660	17557198	17557387

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 74.98.

Top tissues by expression

83 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	74.98	gold quality
colonic epithelium	UBERON:0000397	70.07	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.57	gold quality
urinary bladder	UBERON:0001255	65.49	gold quality
gall bladder	UBERON:0002110	64.60	gold quality
adrenal tissue	UBERON:0018303	62.46	gold quality
calcaneal tendon	UBERON:0003701	61.01	gold quality
monocyte	CL:0000576	60.74	gold quality
smooth muscle tissue	UBERON:0001135	60.00	gold quality
kidney	UBERON:0002113	59.95	gold quality
islet of Langerhans	UBERON:0000006	59.69	gold quality
blood	UBERON:0000178	59.04	gold quality
adult mammalian kidney	UBERON:0000082	58.84	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.64	gold quality
gastrocnemius	UBERON:0001388	58.50	gold quality
uterine cervix	UBERON:0000002	56.43	silver quality
tonsil	UBERON:0002372	56.33	silver quality
fallopian tube	UBERON:0003889	55.52	gold quality
myometrium	UBERON:0001296	55.12	gold quality
heart left ventricle	UBERON:0002084	53.26	gold quality
stomach	UBERON:0000945	52.02	gold quality
tibial artery	UBERON:0007610	51.88	gold quality
corpus callosum	UBERON:0002336	51.29	gold quality
adrenal gland	UBERON:0002369	51.18	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.82	gold quality
left adrenal gland cortex	UBERON:0035825	50.81	gold quality
cortex of kidney	UBERON:0001225	50.59	gold quality
heart	UBERON:0000948	50.43	gold quality
putamen	UBERON:0001874	49.63	gold quality
left adrenal gland	UBERON:0001234	49.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.