NIPAL2-AS1

Summary

NIPAL2-AS1 (NIPAL2 antisense RNA 1, HGNC:56271) is a long non-coding RNA gene on chromosome 8q22.2.

At a glance

• Clinical variants (ClinVar): 6 total

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56271
Approved symbol	NIPAL2-AS1
Name	NIPAL2 antisense RNA 1
Location	8q22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc-POP1-1
Entrez	105375660

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

6 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000022314 (8:98211773 T>G), RS1000035041 (8:98230366 T>C), RS1000106651 (8:98230015 G>A), RS1000120924 (8:98222118 C>G), RS1000162314 (8:98217922 G>T), RS1000194726 (8:98239481 C>T), RS1000201092 (8:98234013 A>G), RS1000212769 (8:98217418 C>G,T), RS1000288881 (8:98194945 A>C,G), RS1000303107 (8:98201706 A>G), RS1000330239 (8:98236550 G>A), RS1000333399 (8:98182448 C>A,T), RS1000345982 (8:98210822 C>G), RS1000378801 (8:98245880 C>G,T), RS1000421845 (8:98233002 G>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.