NIPAL4-DT

Summary

NIPAL4-DT (NIPAL4 divergent transcript, HGNC:55542) is a long non-coding RNA gene on chromosome 5q33.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55542
Approved symbol	NIPAL4-DT
Name	NIPAL4 divergent transcript
Location	5q33.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251405
Ensembl biotype	lncRNA
Entrez	102724404
RNAcentral	URS0000A77265 — lncRNA, 888 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000509655

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000509655 — 2 exons

Exon	Start	End
ENSE00002033934	157363382	157364397
ENSE00002059480	157364526	157365501

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 70.31.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1601 / max 25.2082, expressed in 85 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
64521	0.1601	85

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	70.31	silver quality
colonic epithelium	UBERON:0000397	69.34	silver quality
muscle layer of sigmoid colon	UBERON:0035805	68.14	gold quality
sural nerve	UBERON:0015488	65.19	silver quality
tonsil	UBERON:0002372	61.55	silver quality
testis	UBERON:0000473	61.42	silver quality
colon	UBERON:0001155	60.64	gold quality
blood	UBERON:0000178	60.22	gold quality
urinary bladder	UBERON:0001255	60.06	gold quality
fundus of stomach	UBERON:0001160	59.59	gold quality
intestine	UBERON:0000160	57.72	gold quality
tibial artery	UBERON:0007610	57.13	gold quality
popliteal artery	UBERON:0002250	57.05	gold quality
right coronary artery	UBERON:0001625	56.06	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	55.86	gold quality
lower esophagus muscularis layer	UBERON:0035833	55.84	gold quality
cortical plate	UBERON:0005343	55.83	silver quality
lower esophagus	UBERON:0013473	55.71	gold quality
skeletal muscle tissue	UBERON:0001134	54.67	silver quality
placenta	UBERON:0001987	54.40	gold quality
cortex of kidney	UBERON:0001225	54.18	gold quality
prefrontal cortex	UBERON:0000451	54.14	gold quality
corpus callosum	UBERON:0002336	54.11	gold quality
stromal cell of endometrium	CL:0002255	53.92	silver quality
muscle tissue	UBERON:0002385	53.88	gold quality
esophagus	UBERON:0001043	53.60	gold quality
kidney	UBERON:0002113	53.57	gold quality
substantia nigra	UBERON:0002038	53.42	gold quality
transverse colon	UBERON:0001157	53.29	gold quality
liver	UBERON:0002107	52.98	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.