NIPBL-DT

Summary

NIPBL-DT (NIPBL divergent transcript, HGNC:51293) is a long non-coding RNA gene on chromosome 5p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51293
Approved symbol	NIPBL-DT
Name	NIPBL divergent transcript
Location	5p13.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	NIPBL-AS
Ensembl gene	ENSG00000285967
Ensembl biotype	lncRNA
Entrez	646719
RNAcentral	URS000075BCC2 — lncRNA, 5346 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000647750, ENST00000647824, ENST00000649921, ENST00000805412, ENST00000805413, ENST00000805414

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000647750 — 2 exons

Exon	Start	End
ENSE00003832502	36875671	36876657
ENSE00003832681	36864425	36866026

Expression profiles

Bgee: expression breadth ubiquitous, 138 present calls, max score 99.11.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 8.1639 / max 81.2498, expressed in 1673 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
61329	8.1639	1673

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cerebellar vermis	UBERON:0004720	99.11	gold quality
thymus	UBERON:0002370	98.80	gold quality
quadriceps femoris	UBERON:0001377	93.54	gold quality
cortical plate	UBERON:0005343	88.87	gold quality
calcaneal tendon	UBERON:0003701	86.37	gold quality
ganglionic eminence	UBERON:0004023	85.04	gold quality
ventricular zone	UBERON:0003053	82.68	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.78	gold quality
superior frontal gyrus	UBERON:0002661	81.77	gold quality
cerebellar cortex	UBERON:0002129	81.60	gold quality
cerebellum	UBERON:0002037	81.49	gold quality
cerebellar hemisphere	UBERON:0002245	81.46	gold quality
right hemisphere of cerebellum	UBERON:0014890	81.06	gold quality
corpus callosum	UBERON:0002336	80.89	gold quality
endometrium	UBERON:0001295	79.91	gold quality
mucosa of stomach	UBERON:0001199	79.64	gold quality
prefrontal cortex	UBERON:0000451	79.22	gold quality
spinal cord	UBERON:0002240	78.91	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	78.87	gold quality
Brodmann (1909) area 9	UBERON:0013540	78.83	gold quality
primary visual cortex	UBERON:0002436	78.78	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.65	gold quality
brain	UBERON:0000955	78.48	gold quality
Ammon’s horn	UBERON:0001954	78.44	gold quality
popliteal artery	UBERON:0002250	78.42	gold quality
tibial artery	UBERON:0007610	78.41	gold quality
nucleus accumbens	UBERON:0001882	78.40	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	78.34	gold quality
left ovary	UBERON:0002119	78.33	gold quality
cerebral cortex	UBERON:0000956	78.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.