NLGN4Y-AS1

Summary

NLGN4Y-AS1 (NLGN4Y antisense RNA 1, HGNC:38793) is a long non-coding RNA gene on chromosome Yq11.221.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38793
Approved symbol	NLGN4Y-AS1
Name	NLGN4Y antisense RNA 1
Location	Yq11.221
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228787
Ensembl biotype	lncRNA
Entrez	100874056
RNAcentral	URS0000490E71 — lncRNA, 532 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000434164

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434164 — 4 exons

Exon	Start	End
ENSE00001638780	14804005	14804033
ENSE00001648650	14793642	14793987
ENSE00001750121	14801276	14801344
ENSE00001766520	14798622	14798709

Expression profiles

Bgee: expression breadth broad, 79 present calls, max score 63.90.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1388 / max 12.7116, expressed in 63 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
201259	0.0825	55
201260	0.0563	43

Top tissues by expression

79 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	63.90	gold quality
cortex of kidney	UBERON:0001225	55.54	gold quality
calcaneal tendon	UBERON:0003701	54.86	gold quality
adrenal tissue	UBERON:0018303	53.82	gold quality
islet of Langerhans	UBERON:0000006	53.22	gold quality
kidney	UBERON:0002113	52.75	gold quality
placenta	UBERON:0001987	52.73	gold quality
blood	UBERON:0000178	52.05	silver quality
corpus callosum	UBERON:0002336	51.31	silver quality
gall bladder	UBERON:0002110	50.98	gold quality
prefrontal cortex	UBERON:0000451	50.18	gold quality
liver	UBERON:0002107	49.82	gold quality
superior frontal gyrus	UBERON:0002661	48.37	gold quality
left ovary	UBERON:0002119	48.36	gold quality
cerebellar cortex	UBERON:0002129	48.30	silver quality
cerebellar hemisphere	UBERON:0002245	48.30	silver quality
cerebellum	UBERON:0002037	48.28	silver quality
amygdala	UBERON:0001876	48.09	gold quality
gastrocnemius	UBERON:0001388	47.44	silver quality
primary visual cortex	UBERON:0002436	47.25	silver quality
Brodmann (1909) area 9	UBERON:0013540	47.16	gold quality
adrenal gland	UBERON:0002369	47.15	gold quality
left adrenal gland cortex	UBERON:0035825	46.98	gold quality
substantia nigra	UBERON:0002038	46.69	gold quality
nucleus accumbens	UBERON:0001882	46.55	gold quality
left adrenal gland	UBERON:0001234	46.31	gold quality
putamen	UBERON:0001874	46.07	gold quality
right hemisphere of cerebellum	UBERON:0014890	45.92	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	45.48	gold quality
brain	UBERON:0000955	45.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.