NMBR-AS1

Summary

NMBR-AS1 (NMBR antisense RNA 1, HGNC:40406) is a long non-coding RNA gene on chromosome 6q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40406
Approved symbol	NMBR-AS1
Name	NMBR antisense RNA 1
Location	6q24.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-137J7.2
Ensembl gene	ENSG00000236822
Ensembl biotype	lncRNA
Entrez	111216274
RNAcentral	URS000041EB5B — ncRNA, 222 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000454401

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000454401 — 2 exons

Exon	Start	End
ENSE00001787807	142089140	142089219
ENSE00001796667	142088233	142088374

Expression profiles

Bgee: expression breadth broad, 61 present calls, max score 78.99.

Top tissues by expression

61 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.99	gold quality
skeletal muscle tissue	UBERON:0001134	75.09	gold quality
sural nerve	UBERON:0015488	67.53	gold quality
corpus callosum	UBERON:0002336	67.50	gold quality
prefrontal cortex	UBERON:0000451	67.47	gold quality
monocyte	CL:0000576	66.12	gold quality
islet of Langerhans	UBERON:0000006	64.37	gold quality
gastrocnemius	UBERON:0001388	61.99	gold quality
gall bladder	UBERON:0002110	61.64	gold quality
right atrium auricular region	UBERON:0006631	59.15	gold quality
lung	UBERON:0002048	58.94	gold quality
transverse colon	UBERON:0001157	58.88	gold quality
tibial artery	UBERON:0007610	58.76	gold quality
heart left ventricle	UBERON:0002084	57.47	gold quality
body of stomach	UBERON:0001161	56.73	gold quality
stomach	UBERON:0000945	56.37	gold quality
Brodmann (1909) area 9	UBERON:0013540	55.38	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	55.17	gold quality
calcaneal tendon	UBERON:0003701	55.15	gold quality
esophagus mucosa	UBERON:0002469	54.74	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	54.70	gold quality
ascending aorta	UBERON:0001496	54.64	gold quality
subcutaneous adipose tissue	UBERON:0002190	54.35	gold quality
muscle layer of sigmoid colon	UBERON:0035805	54.11	gold quality
hypothalamus	UBERON:0001898	53.76	gold quality
vagina	UBERON:0000996	53.63	gold quality
lower esophagus	UBERON:0013473	53.58	gold quality
lower esophagus muscularis layer	UBERON:0035833	53.43	gold quality
nucleus accumbens	UBERON:0001882	53.36	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.