NOP14-AS1
gene geneOn this page
Also known as RES4-24
Summary
NOP14-AS1 (NOP14 antisense RNA 1, HGNC:20205) is a long non-coding RNA gene on chromosome 4p16.3.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:20205 |
| Approved symbol | NOP14-AS1 |
| Name | NOP14 antisense RNA 1 |
| Location | 4p16.3 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Aliases | RES4-24 |
| Ensembl gene | ENSG00000249673 |
| Ensembl biotype | lncRNA |
| Entrez | 317648 |
| RNAcentral | URS0000812208 — lncRNA, 3881 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 30 — 30 lncRNA
ENST00000503709, ENST00000505731, ENST00000507702, ENST00000507999, ENST00000512712, ENST00000512802, ENST00000515194, ENST00000658490, ENST00000662831, ENST00000663849, ENST00000664833, ENST00000671407, ENST00000671608, ENST00000685071, ENST00000701748, ENST00000733083, ENST00000733085, ENST00000733086, ENST00000733088, ENST00000733090, ENST00000733092, ENST00000733095, ENST00000733097, ENST00000733099, ENST00000733101, ENST00000733103, ENST00000733105, ENST00000733107, ENST00000733109, ENST00000733111
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000503709 — 4 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002019812 | 2961354 | 2961738 |
| ENSE00002026512 | 2950153 | 2950556 |
| ENSE00002036122 | 2937266 | 2937844 |
| ENSE00002074669 | 2946873 | 2947120 |
Expression profiles
Bgee: expression breadth ubiquitous, 183 present calls, max score 82.94.
FANTOM5 (CAGE): breadth ubiquitous, TPM avg 12.7407 / max 148.3016, expressed in 1782 samples.
FANTOM5 promoters (3 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 46662 | 12.4492 | 1782 |
| 46663 | 0.1766 | 77 |
| 46664 | 0.1149 | 55 |
Top tissues by expression
287 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| cortical plate | UBERON:0005343 | 82.94 | gold quality |
| granulocyte | CL:0000094 | 81.62 | gold quality |
| mucosa of stomach | UBERON:0001199 | 81.57 | gold quality |
| popliteal artery | UBERON:0002250 | 81.47 | gold quality |
| tibial artery | UBERON:0007610 | 81.45 | gold quality |
| adenohypophysis | UBERON:0002196 | 81.07 | gold quality |
| left lobe of thyroid gland | UBERON:0001120 | 80.68 | gold quality |
| right hemisphere of cerebellum | UBERON:0014890 | 80.67 | gold quality |
| aorta | UBERON:0000947 | 80.58 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 80.49 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 80.48 | gold quality |
| right coronary artery | UBERON:0001625 | 80.37 | gold quality |
| left ovary | UBERON:0002119 | 80.37 | gold quality |
| ganglionic eminence | UBERON:0004023 | 80.32 | gold quality |
| right lobe of thyroid gland | UBERON:0001119 | 80.15 | gold quality |
| left coronary artery | UBERON:0001626 | 80.09 | gold quality |
| thoracic aorta | UBERON:0001515 | 79.91 | gold quality |
| ascending aorta | UBERON:0001496 | 79.86 | gold quality |
| cerebellar hemisphere | UBERON:0002245 | 79.86 | gold quality |
| C1 segment of cervical spinal cord | UBERON:0006469 | 79.81 | gold quality |
| body of stomach | UBERON:0001161 | 79.78 | gold quality |
| thyroid gland | UBERON:0002046 | 79.76 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 79.76 | gold quality |
| lower esophagus | UBERON:0013473 | 79.72 | gold quality |
| cerebellar cortex | UBERON:0002129 | 79.69 | gold quality |
| body of uterus | UBERON:0009853 | 79.61 | gold quality |
| skin of abdomen | UBERON:0001416 | 79.30 | gold quality |
| skin of leg | UBERON:0001511 | 79.10 | gold quality |
| vagina | UBERON:0000996 | 79.05 | gold quality |
| endocervix | UBERON:0000458 | 79.03 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 3.12 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): Huntington disease