NOP53-AS1

Summary

NOP53-AS1 (NOP53 antisense RNA 1, HGNC:51587) is a long non-coding RNA gene on chromosome 19q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51587
Approved symbol	NOP53-AS1
Name	NOP53 antisense RNA 1
Location	19q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000269656
Ensembl biotype	lncRNA
Entrez	106144593
RNAcentral	URS000036E956 — lncRNA, 540 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000602048, ENST00000782631, ENST00000782632

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000602048 — 3 exons

Exon	Start	End
ENSE00003079039	47768622	47768840
ENSE00003160016	47766741	47766819
ENSE00003207840	47757036	47757277

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 83.66.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.66	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.76	silver quality
sural nerve	UBERON:0015488	73.80	gold quality
colonic epithelium	UBERON:0000397	72.19	gold quality
ventricular zone	UBERON:0003053	71.25	gold quality
ganglionic eminence	UBERON:0004023	66.61	gold quality
cortical plate	UBERON:0005343	64.95	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.54	gold quality
duodenum	UBERON:0002114	62.50	gold quality
bone marrow	UBERON:0002371	61.87	gold quality
urinary bladder	UBERON:0001255	61.76	gold quality
skeletal muscle tissue	UBERON:0001134	61.64	gold quality
gall bladder	UBERON:0002110	61.14	gold quality
muscle of leg	UBERON:0001383	60.91	gold quality
monocyte	CL:0000576	60.85	gold quality
body of pancreas	UBERON:0001150	60.70	gold quality
granulocyte	CL:0000094	60.68	gold quality
gastrocnemius	UBERON:0001388	60.64	gold quality
pancreas	UBERON:0001264	59.95	gold quality
ovary	UBERON:0000992	59.92	gold quality
left ovary	UBERON:0002119	59.91	gold quality
myometrium	UBERON:0001296	59.39	gold quality
lymph node	UBERON:0000029	59.36	gold quality
placenta	UBERON:0001987	59.18	gold quality
stromal cell of endometrium	CL:0002255	59.09	gold quality
right ovary	UBERON:0002118	58.50	gold quality
zone of skin	UBERON:0000014	58.42	gold quality
skin of abdomen	UBERON:0001416	58.29	gold quality
skin of leg	UBERON:0001511	58.20	gold quality
endocervix	UBERON:0000458	58.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.