NPAS2-AS1

Summary

NPAS2-AS1 (NPAS2 antisense RNA 1, HGNC:40408) is a long non-coding RNA gene on chromosome 2q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40408
Approved symbol	NPAS2-AS1
Name	NPAS2 antisense RNA 1
Location	2q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230140
Ensembl biotype	lncRNA
Entrez	101927142
RNAcentral	URS000075CE7A — lncRNA, 771 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000433012, ENST00000439150, ENST00000446644, ENST00000652285

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433012 — 4 exons

Exon	Start	End
ENSE00001632618	100976716	100977766
ENSE00001725136	100975285	100975413
ENSE00003843310	100975533	100975668
ENSE00003874412	100972652	100972843

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 86.84.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	86.84	gold quality
cerebellar vermis	UBERON:0004720	85.28	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.39	silver quality
thymus	UBERON:0002370	70.18	silver quality
cortical plate	UBERON:0005343	65.85	gold quality
skeletal muscle tissue	UBERON:0001134	65.27	gold quality
left testis	UBERON:0004533	64.80	gold quality
testis	UBERON:0000473	64.38	gold quality
right testis	UBERON:0004534	62.99	gold quality
tonsil	UBERON:0002372	62.52	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.99	gold quality
lower esophagus mucosa	UBERON:0035834	61.21	gold quality
ganglionic eminence	UBERON:0004023	60.92	gold quality
stromal cell of endometrium	CL:0002255	56.81	gold quality
bone marrow	UBERON:0002371	56.77	silver quality
muscle of leg	UBERON:0001383	53.30	gold quality
gastrocnemius	UBERON:0001388	53.01	gold quality
blood	UBERON:0000178	52.84	gold quality
lymph node	UBERON:0000029	52.77	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.57	gold quality
liver	UBERON:0002107	52.08	silver quality
superior frontal gyrus	UBERON:0002661	52.08	gold quality
monocyte	CL:0000576	51.49	gold quality
gall bladder	UBERON:0002110	51.41	gold quality
urinary bladder	UBERON:0001255	51.17	gold quality
prostate gland	UBERON:0002367	50.89	gold quality
prefrontal cortex	UBERON:0000451	50.83	gold quality
esophagus mucosa	UBERON:0002469	50.49	gold quality
right lobe of liver	UBERON:0001114	50.45	silver quality
apex of heart	UBERON:0002098	49.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.