NR3C2-DT

Summary

NR3C2-DT (NR3C2 divergent transcript, HGNC:58892) is a long non-coding RNA gene on chromosome 4q31.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58892
Approved symbol	NR3C2-DT
Name	NR3C2 divergent transcript
Location	4q31.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000287292
Ensembl biotype	lncRNA
Entrez	107986195

Gene structure

Transcript identifiers

Ensembl transcripts: 21 — 21 lncRNA

ENST00000661928, ENST00000669991, ENST00000777253, ENST00000777254, ENST00000817567, ENST00000817568, ENST00000817569, ENST00000817570, ENST00000817571, ENST00000817572, ENST00000817573, ENST00000817574, ENST00000817575, ENST00000817576, ENST00000817577, ENST00000817578, ENST00000817579, ENST00000817580, ENST00000817581, ENST00000817582, ENST00000817583

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000661928 — 4 exons

Exon	Start	End
ENSE00003854521	148866757	148866881
ENSE00003861076	148445767	148445870
ENSE00003867977	149023304	149024624
ENSE00003886874	148544467	148544584

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 77.13.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.13	gold quality
ganglionic eminence	UBERON:0004023	62.95	gold quality
islet of Langerhans	UBERON:0000006	59.87	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.66	gold quality
ventricular zone	UBERON:0003053	57.16	silver quality
hindlimb stylopod muscle	UBERON:0004252	54.56	silver quality
leukocyte	CL:0000738	54.46	silver quality
calcaneal tendon	UBERON:0003701	53.52	silver quality
skeletal muscle tissue	UBERON:0001134	53.28	gold quality
corpus callosum	UBERON:0002336	53.12	gold quality
thyroid gland	UBERON:0002046	52.89	gold quality
pancreas	UBERON:0001264	52.73	gold quality
tonsil	UBERON:0002372	52.23	gold quality
prefrontal cortex	UBERON:0000451	52.11	gold quality
left lobe of thyroid gland	UBERON:0001120	52.11	gold quality
endometrium	UBERON:0001295	52.02	gold quality
fallopian tube	UBERON:0003889	51.66	gold quality
right atrium auricular region	UBERON:0006631	51.12	gold quality
monocyte	CL:0000576	51.00	silver quality
heart	UBERON:0000948	50.26	gold quality
superior frontal gyrus	UBERON:0002661	50.12	gold quality
heart left ventricle	UBERON:0002084	50.01	gold quality
adult mammalian kidney	UBERON:0000082	49.90	gold quality
right lobe of thyroid gland	UBERON:0001119	49.79	gold quality
gall bladder	UBERON:0002110	49.61	gold quality
primary visual cortex	UBERON:0002436	49.26	silver quality
urinary bladder	UBERON:0001255	49.12	gold quality
frontal cortex	UBERON:0001870	48.75	gold quality
left adrenal gland cortex	UBERON:0035825	48.74	gold quality
kidney	UBERON:0002113	48.56	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.