NRAL

Summary

NRAL (NRF2 regulation associated lncRNA, HGNC:56652) is a long non-coding RNA gene on chromosome 2q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56652
Approved symbol	NRAL
Name	NRF2 regulation associated lncRNA
Location	2q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229434
Ensembl biotype	lncRNA
Entrez	128071539
RNAcentral	URS00001CC87D — lncRNA, 495 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000412153

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412153 — 2 exons

Exon	Start	End
ENSE00001633624	176507500	176507702
ENSE00001744068	176506245	176506536

Expression profiles

Bgee: expression breadth broad, 47 present calls, max score 62.95.

Top tissues by expression

47 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
substantia nigra	UBERON:0002038	62.95	gold quality
blood	UBERON:0000178	56.59	silver quality
calcaneal tendon	UBERON:0003701	55.86	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	55.03	gold quality
thoracic mammary gland	UBERON:0005200	51.79	gold quality
myometrium	UBERON:0001296	50.88	gold quality
monocyte	CL:0000576	50.86	silver quality
gastrocnemius	UBERON:0001388	50.85	silver quality
right testis	UBERON:0004534	48.93	gold quality
putamen	UBERON:0001874	47.59	gold quality
esophagus	UBERON:0001043	47.53	gold quality
testis	UBERON:0000473	47.35	gold quality
left testis	UBERON:0004533	47.08	gold quality
esophagus mucosa	UBERON:0002469	46.63	gold quality
heart left ventricle	UBERON:0002084	46.42	gold quality
anterior cingulate cortex	UBERON:0009835	46.40	gold quality
multicellular organism	UBERON:0000468	46.27	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	45.72	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.71	gold quality
ascending aorta	UBERON:0001496	45.19	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.12	gold quality
right lobe of liver	UBERON:0001114	44.86	silver quality
thoracic aorta	UBERON:0001515	44.71	gold quality
tibial artery	UBERON:0007610	43.81	silver quality
body of uterus	UBERON:0009853	43.77	gold quality
zone of skin	UBERON:0000014	43.20	silver quality
vagina	UBERON:0000996	43.19	gold quality
amygdala	UBERON:0001876	42.93	gold quality
minor salivary gland	UBERON:0001830	42.85	silver quality
transverse colon	UBERON:0001157	42.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.