NREP-AS1

Summary

NREP-AS1 (NREP antisense RNA 1, HGNC:40780) is a long non-coding RNA gene on chromosome 5q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40780
Approved symbol	NREP-AS1
Name	NREP antisense RNA 1
Location	5q22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250095
Ensembl biotype	lncRNA
Entrez	100873948
RNAcentral	URS0000759A1F — lncRNA, 624 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000503242, ENST00000507222, ENST00000508389

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503242 — 3 exons

Exon	Start	End
ENSE00002027179	112017140	112017309
ENSE00002031711	111974375	111974506
ENSE00002058005	111969452	111969560

Expression profiles

Bgee: expression breadth broad, 71 present calls, max score 92.40.

Top tissues by expression

76 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.40	gold quality
caudate nucleus	UBERON:0001873	85.64	gold quality
cerebellar vermis	UBERON:0004720	85.54	silver quality
corpus callosum	UBERON:0002336	72.57	gold quality
liver	UBERON:0002107	71.11	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.90	gold quality
calcaneal tendon	UBERON:0003701	67.13	gold quality
islet of Langerhans	UBERON:0000006	64.74	gold quality
skeletal muscle tissue	UBERON:0001134	62.96	silver quality
prefrontal cortex	UBERON:0000451	61.74	gold quality
thymus	UBERON:0002370	59.97	silver quality
bone marrow	UBERON:0002371	59.83	silver quality
pancreas	UBERON:0001264	59.77	gold quality
spleen	UBERON:0002106	57.89	silver quality
adrenal tissue	UBERON:0018303	56.64	gold quality
myometrium	UBERON:0001296	56.58	gold quality
tonsil	UBERON:0002372	56.35	silver quality
prostate gland	UBERON:0002367	55.26	gold quality
monocyte	CL:0000576	54.57	gold quality
blood	UBERON:0000178	54.35	silver quality
amygdala	UBERON:0001876	54.26	gold quality
body of pancreas	UBERON:0001150	52.89	gold quality
rectum	UBERON:0001052	52.75	gold quality
endometrium	UBERON:0001295	52.38	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	51.95	gold quality
adenohypophysis	UBERON:0002196	51.79	gold quality
left testis	UBERON:0004533	51.13	gold quality
kidney	UBERON:0002113	50.62	silver quality
subcutaneous adipose tissue	UBERON:0002190	50.59	gold quality
testis	UBERON:0000473	50.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.92

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.