NRGN-AS1

Summary

NRGN-AS1 (NRGN antisense RNA 1, HGNC:58070) is a long non-coding RNA gene on chromosome 11q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58070
Approved symbol	NRGN-AS1
Name	NRGN antisense RNA 1
Location	11q24.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-677M14.2, Nrgn-AS
Ensembl gene	ENSG00000255045
Ensembl biotype	lncRNA
Entrez	137233470
RNAcentral	URS0002A147CA — lncRNA, 1003 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000531241, ENST00000844371

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000531241 — 3 exons

Exon	Start	End
ENSE00002201428	124745915	124745998
ENSE00004271067	124744634	124744895
ENSE00004271068	124746239	124746678

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 89.17.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.17	gold quality
primary visual cortex	UBERON:0002436	85.34	gold quality
superior frontal gyrus	UBERON:0002661	82.22	gold quality
right uterine tube	UBERON:0001302	80.15	gold quality
right frontal lobe	UBERON:0002810	79.52	gold quality
Brodmann (1909) area 9	UBERON:0013540	75.83	gold quality
frontal cortex	UBERON:0001870	75.31	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	74.54	gold quality
right lobe of thyroid gland	UBERON:0001119	73.94	gold quality
thyroid gland	UBERON:0002046	73.79	gold quality
monocyte	CL:0000576	73.24	gold quality
left lobe of thyroid gland	UBERON:0001120	73.13	gold quality
leukocyte	CL:0000738	72.86	gold quality
putamen	UBERON:0001874	72.80	gold quality
prefrontal cortex	UBERON:0000451	72.10	gold quality
cerebral cortex	UBERON:0000956	71.93	gold quality
right lung	UBERON:0002167	70.54	gold quality
caudate nucleus	UBERON:0001873	70.14	gold quality
lower esophagus mucosa	UBERON:0035834	70.04	gold quality
tibial artery	UBERON:0007610	68.25	gold quality
popliteal artery	UBERON:0002250	68.20	gold quality
gall bladder	UBERON:0002110	67.98	gold quality
anterior cingulate cortex	UBERON:0009835	67.88	gold quality
mucosa of transverse colon	UBERON:0004991	67.73	gold quality
sural nerve	UBERON:0015488	67.65	gold quality
bone marrow	UBERON:0002371	67.41	gold quality
rectum	UBERON:0001052	66.93	gold quality
upper lobe of left lung	UBERON:0008952	66.91	gold quality
brain	UBERON:0000955	66.70	gold quality
granulocyte	CL:0000094	66.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.92

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.