NRXN2-AS1

Summary

NRXN2-AS1 (NRXN2 antisense RNA 1, HGNC:40416) is a long non-coding RNA gene on chromosome 11q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40416
Approved symbol	NRXN2-AS1
Name	NRXN2 antisense RNA 1
Location	11q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237410
Ensembl biotype	lncRNA
Entrez	107984337
RNAcentral	URS000060A110 — lncRNA, 469 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000433606

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433606 — 2 exons

Exon	Start	End
ENSE00001699423	64659393	64659681
ENSE00001712459	64646399	64646578

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 83.87.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.87	gold quality
cortical plate	UBERON:0005343	72.94	gold quality
right hemisphere of cerebellum	UBERON:0014890	72.86	gold quality
cerebellar hemisphere	UBERON:0002245	72.15	gold quality
cerebellar cortex	UBERON:0002129	71.92	gold quality
cerebellum	UBERON:0002037	71.88	gold quality
bone marrow cell	CL:0002092	70.20	silver quality
ganglionic eminence	UBERON:0004023	70.03	gold quality
ventricular zone	UBERON:0003053	69.78	gold quality
descending thoracic aorta	UBERON:0002345	68.08	gold quality
thoracic aorta	UBERON:0001515	66.49	gold quality
ascending aorta	UBERON:0001496	66.11	gold quality
bone marrow	UBERON:0002371	65.92	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.86	gold quality
Ammon’s horn	UBERON:0001954	62.48	gold quality
skeletal muscle tissue	UBERON:0001134	61.75	gold quality
placenta	UBERON:0001987	61.75	gold quality
anterior cingulate cortex	UBERON:0009835	61.44	gold quality
substantia nigra	UBERON:0002038	61.19	gold quality
brain	UBERON:0000955	61.04	gold quality
left testis	UBERON:0004533	60.91	gold quality
amygdala	UBERON:0001876	60.88	gold quality
prefrontal cortex	UBERON:0000451	60.86	gold quality
testis	UBERON:0000473	60.83	gold quality
frontal cortex	UBERON:0001870	60.60	gold quality
right frontal lobe	UBERON:0002810	60.59	gold quality
cerebral cortex	UBERON:0000956	60.55	gold quality
nucleus accumbens	UBERON:0001882	60.53	gold quality
right testis	UBERON:0004534	59.79	gold quality
hypothalamus	UBERON:0001898	59.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.