NRXN3-AS1

Summary

NRXN3-AS1 (NRXN3 antisense RNA 1, HGNC:58459) is a long non-coding RNA gene on chromosome 14q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58459
Approved symbol	NRXN3-AS1
Name	NRXN3 antisense RNA 1
Location	14q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258829
Ensembl biotype	lncRNA
Entrez	124903353

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000553348, ENST00000556145

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553348 — 2 exons

Exon	Start	End
ENSE00002480158	79074548	79074762
ENSE00002520278	79072132	79072475

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 80.77.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	80.77	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.36	gold quality
bone marrow cell	CL:0002092	69.82	silver quality
tibial nerve	UBERON:0001323	62.75	gold quality
superior frontal gyrus	UBERON:0002661	59.07	gold quality
blood	UBERON:0000178	57.25	gold quality
liver	UBERON:0002107	57.02	gold quality
cortex of kidney	UBERON:0001225	56.04	gold quality
prefrontal cortex	UBERON:0000451	54.85	gold quality
monocyte	CL:0000576	54.44	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.48	gold quality
primary visual cortex	UBERON:0002436	52.46	gold quality
adrenal tissue	UBERON:0018303	51.99	gold quality
kidney	UBERON:0002113	51.47	gold quality
lung	UBERON:0002048	51.46	silver quality
islet of Langerhans	UBERON:0000006	51.08	gold quality
skin of leg	UBERON:0001511	50.91	gold quality
adult mammalian kidney	UBERON:0000082	50.40	gold quality
zone of skin	UBERON:0000014	50.02	gold quality
body of stomach	UBERON:0001161	49.10	gold quality
skin of abdomen	UBERON:0001416	48.64	gold quality
pancreas	UBERON:0001264	48.23	gold quality
Ammon’s horn	UBERON:0001954	47.90	gold quality
tibial artery	UBERON:0007610	47.21	gold quality
esophagus mucosa	UBERON:0002469	47.00	gold quality
gastrocnemius	UBERON:0001388	46.91	silver quality
cerebellar cortex	UBERON:0002129	46.67	silver quality
calcaneal tendon	UBERON:0003701	46.48	silver quality
multicellular organism	UBERON:0000468	46.25	gold quality
prostate gland	UBERON:0002367	45.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.