NRXN3-AS2

Summary

NRXN3-AS2 (NRXN3 antisense RNA 2, HGNC:58461) is a long non-coding RNA gene on chromosome 14q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58461
Approved symbol	NRXN3-AS2
Name	NRXN3 antisense RNA 2
Location	14q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258874
Ensembl biotype	lncRNA
Entrez	105370589

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000555680, ENST00000838196, ENST00000838197, ENST00000838198

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000555680 — 2 exons

Exon	Start	End
ENSE00004259375	78709816	78709986
ENSE00004259377	78703608	78703849

Expression profiles

Bgee: expression breadth broad, 59 present calls, max score 88.73.

Top tissues by expression

59 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	88.73	gold quality
left testis	UBERON:0004533	88.28	gold quality
testis	UBERON:0000473	88.00	gold quality
multicellular organism	UBERON:0000468	66.48	gold quality
gastrocnemius	UBERON:0001388	60.60	gold quality
prefrontal cortex	UBERON:0000451	58.60	gold quality
blood	UBERON:0000178	56.28	gold quality
primary visual cortex	UBERON:0002436	56.28	gold quality
endometrium	UBERON:0001295	54.25	gold quality
monocyte	CL:0000576	52.99	gold quality
corpus callosum	UBERON:0002336	52.97	gold quality
ascending aorta	UBERON:0001496	50.72	gold quality
right ovary	UBERON:0002118	50.66	gold quality
thoracic aorta	UBERON:0001515	50.54	gold quality
adult mammalian kidney	UBERON:0000082	50.22	gold quality
cerebellum	UBERON:0002037	49.35	gold quality
body of pancreas	UBERON:0001150	49.30	gold quality
tibial artery	UBERON:0007610	48.45	gold quality
right coronary artery	UBERON:0001625	47.87	gold quality
left adrenal gland cortex	UBERON:0035825	47.85	gold quality
left adrenal gland	UBERON:0001234	47.83	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	47.82	gold quality
body of stomach	UBERON:0001161	47.70	gold quality
esophagus mucosa	UBERON:0002469	47.60	gold quality
omental fat pad	UBERON:0010414	47.23	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	46.62	gold quality
heart	UBERON:0000948	46.27	gold quality
muscle layer of sigmoid colon	UBERON:0035805	46.23	gold quality
subcutaneous adipose tissue	UBERON:0002190	46.14	gold quality
substantia nigra	UBERON:0002038	46.06	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.