NRXN3-AS3

Summary

NRXN3-AS3 (NRXN3 antisense RNA 3, HGNC:58616) is a long non-coding RNA gene on chromosome 14q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58616
Approved symbol	NRXN3-AS3
Name	NRXN3 antisense RNA 3
Location	14q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259106
Ensembl biotype	lncRNA
Entrez	105370583

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000553812

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553812 — 3 exons

Exon	Start	End
ENSE00002488952	79633288	79633311
ENSE00002517224	79611418	79611830
ENSE00002526392	79632278	79632391

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 81.72.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.72	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.62	gold quality
sural nerve	UBERON:0015488	72.23	gold quality
ganglionic eminence	UBERON:0004023	62.94	gold quality
calcaneal tendon	UBERON:0003701	58.04	gold quality
skeletal muscle tissue	UBERON:0001134	57.14	gold quality
blood	UBERON:0000178	53.91	gold quality
hindlimb stylopod muscle	UBERON:0004252	53.76	gold quality
leukocyte	CL:0000738	53.35	gold quality
bone marrow	UBERON:0002371	53.19	silver quality
lymph node	UBERON:0000029	53.04	gold quality
monocyte	CL:0000576	52.61	gold quality
prefrontal cortex	UBERON:0000451	52.33	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.13	gold quality
muscle of leg	UBERON:0001383	52.12	gold quality
liver	UBERON:0002107	51.61	gold quality
right lobe of liver	UBERON:0001114	51.58	gold quality
corpus callosum	UBERON:0002336	51.56	gold quality
cortex of kidney	UBERON:0001225	51.43	gold quality
gastrocnemius	UBERON:0001388	50.95	gold quality
urinary bladder	UBERON:0001255	50.90	gold quality
islet of Langerhans	UBERON:0000006	50.68	gold quality
primary visual cortex	UBERON:0002436	50.28	silver quality
placenta	UBERON:0001987	49.91	gold quality
superior frontal gyrus	UBERON:0002661	49.88	gold quality
kidney	UBERON:0002113	49.35	silver quality
endometrium	UBERON:0001295	48.83	gold quality
cerebellum	UBERON:0002037	48.74	silver quality
cerebellar cortex	UBERON:0002129	48.69	silver quality
smooth muscle tissue	UBERON:0001135	48.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.