NSMCE1-DT

Summary

NSMCE1-DT (NSMCE1 divergent transcript, HGNC:51368) is a long non-coding RNA gene on chromosome 16p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51368
Approved symbol	NSMCE1-DT
Name	NSMCE1 divergent transcript
Location	16p12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245888
Ensembl biotype	lncRNA
Entrez	400512
RNAcentral	URS000075EF15 — lncRNA, 631 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000499939, ENST00000565060, ENST00000566535, ENST00000566854, ENST00000661766, ENST00000833004, ENST00000833005, ENST00000833006, ENST00000833007, ENST00000833008

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499939 — 2 exons

Exon	Start	End
ENSE00004249092	27269671	27271976
ENSE00004249095	27268850	27269156

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 81.30.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0646 / max 38.0461, expressed in 15 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
153312	0.0327	9
153311	0.0184	7
153313	0.0135	4

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	81.30	gold quality
left testis	UBERON:0004533	80.65	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.46	gold quality
testis	UBERON:0000473	77.27	gold quality
right lobe of liver	UBERON:0001114	75.52	gold quality
right lung	UBERON:0002167	75.40	gold quality
right uterine tube	UBERON:0001302	73.74	gold quality
bone marrow cell	CL:0002092	71.67	gold quality
lower esophagus mucosa	UBERON:0035834	70.85	gold quality
right lobe of thyroid gland	UBERON:0001119	69.97	gold quality
stromal cell of endometrium	CL:0002255	69.36	gold quality
left lobe of thyroid gland	UBERON:0001120	69.27	gold quality
rectum	UBERON:0001052	69.15	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	69.12	gold quality
thyroid gland	UBERON:0002046	69.01	gold quality
leukocyte	CL:0000738	68.97	gold quality
monocyte	CL:0000576	68.96	gold quality
lower esophagus muscularis layer	UBERON:0035833	68.64	gold quality
lower esophagus	UBERON:0013473	68.62	gold quality
blood	UBERON:0000178	67.34	gold quality
gall bladder	UBERON:0002110	67.14	gold quality
prostate gland	UBERON:0002367	67.08	gold quality
mucosa of transverse colon	UBERON:0004991	67.08	gold quality
right adrenal gland cortex	UBERON:0035827	66.96	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.91	gold quality
smooth muscle tissue	UBERON:0001135	66.36	gold quality
granulocyte	CL:0000094	66.00	gold quality
metanephros cortex	UBERON:0010533	65.95	gold quality
body of stomach	UBERON:0001161	65.68	gold quality
upper lobe of left lung	UBERON:0008952	65.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	12.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.