NTRAS

Summary

NTRAS (non-coding transcript regulating alternative splicing, HGNC:52478) is a long non-coding RNA gene on chromosome 1q32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52478
Approved symbol	NTRAS
Name	non-coding transcript regulating alternative splicing
Location	1q32.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-354K1.1
Ensembl gene	ENSG00000227764
Ensembl biotype	lncRNA
Entrez	105748977
RNAcentral	URS00008E39CF — lncRNA, 815 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 14 lncRNA, 1 retained_intron

ENST00000412871, ENST00000430123, ENST00000653761, ENST00000653827, ENST00000654864, ENST00000660041, ENST00000661623, ENST00000661855, ENST00000664125, ENST00000666922, ENST00000667263, ENST00000667986, ENST00000670044, ENST00000722507, ENST00000722508

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412871 — 2 exons

Exon	Start	End
ENSE00001703036	211639695	211640360
ENSE00001729076	211654044	211654581

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 56.02.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0442 / max 5.6099, expressed in 18 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
8429	0.0442	18

Top tissues by expression

87 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	56.02	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.29	gold quality
urinary bladder	UBERON:0001255	55.27	gold quality
amygdala	UBERON:0001876	54.80	gold quality
blood	UBERON:0000178	54.76	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.29	gold quality
substantia nigra	UBERON:0002038	53.08	gold quality
liver	UBERON:0002107	53.07	silver quality
Ammon’s horn	UBERON:0001954	52.78	gold quality
myometrium	UBERON:0001296	51.88	gold quality
hypothalamus	UBERON:0001898	51.70	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	51.53	gold quality
calcaneal tendon	UBERON:0003701	51.14	silver quality
cerebral cortex	UBERON:0000956	50.91	gold quality
brain	UBERON:0000955	50.86	gold quality
prefrontal cortex	UBERON:0000451	50.77	gold quality
Brodmann (1909) area 9	UBERON:0013540	50.77	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	50.40	silver quality
putamen	UBERON:0001874	50.34	gold quality
right frontal lobe	UBERON:0002810	50.19	gold quality
caudate nucleus	UBERON:0001873	50.15	gold quality
frontal cortex	UBERON:0001870	50.08	gold quality
cerebellar hemisphere	UBERON:0002245	49.91	gold quality
anterior cingulate cortex	UBERON:0009835	49.07	gold quality
primary visual cortex	UBERON:0002436	48.42	silver quality
endocervix	UBERON:0000458	48.39	gold quality
islet of Langerhans	UBERON:0000006	48.24	gold quality
placenta	UBERON:0001987	48.19	gold quality
right hemisphere of cerebellum	UBERON:0014890	48.14	gold quality
fallopian tube	UBERON:0003889	48.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• RELA promotes hypoxia-induced angiogenesis in human umbilical vascular endothelial cells via LINC01693/miR-302d/CXCL12 axis. (PMID:30937967)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.